N-Benzylmaleimide - ≥98% , CAS No.1631-26-1

CAS: 1631-26-1 Cat. No.: N131913 Molecular Weight: 187.2 EC Number: 216-631-1

GRADE & PURITY ≥98%

Synonyms

6G-925 | Z56899082 | BB 0259301 | 1H-Pyrrole-2,5-dione, 1-(phenylmethyl)- | AKOS000248191 | p,p'-Azoxyanisole | 4-(phenyldiazenyl)benzoic acid | UNII-UPL94A7TQH | W-107957 | 1-benzyl-2,5-dihydro-1H-pyrrole-2,5-dione | N-BENZYL MALEIMIDE | DTXSID50167511 |

Storage

Room temperature

Shipped In

Normal

Specifications

Synonyms

6G-925 | Z56899082 | BB 0259301 | 1H-Pyrrole-2, 5-dione, 1-(phenylmethyl)- | AKOS000248191 | p, p'-Azoxyanisole | 4-(phenyldiazenyl)benzoic acid | UNII-UPL94A7TQH | W-107957 | 1-benzyl-2, 5-dihydro-1H-pyrrole-2, 5-dione | N-BENZYL MALEIMIDE | DTXSID50167511 |

Specifications & Purity

≥98%

Storage

Room temperature

Shipped In

Normal

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488184885
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488184885
• Canonical Smiles: C1=CC=C(C=C1)CN2C(=O)C=CC2=O
• IUPAC Name: 1-benzylpyrrole-2,5-dione
• InChIKey: MKRBAPNEJMFMHU-UHFFFAOYSA-N
• INCHI: 1S/C11H9NO2/c13-10-6-7-11(14)12(10)8-9-4-2-1-3-5-9/h1-7H,8H2
• Isomeric SMILES: C1=CC=C(C=C1)CN2C(=O)C=CC2=O
• WGK Germany: 3
• Molecular Weight: 187.2
• Reaxy-Rn: 135801
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=135801&ln=

Associated Targets(Human)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

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PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

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CTSB Tchem Cathepsin B (3822 Activities)

Discover Target: CTSB

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PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)

Discover Target: PLK1

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MCF7 (126967 Activities)

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HepG2 (196354 Activities)

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NCI-H460 (60772 Activities)

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SF-268 (49410 Activities)

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FEN1 Tchem Flap endonuclease 1 (12055 Activities)

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MGLL Tchem Monoglyceride lipase (1909 Activities)

Discover Target: MGLL

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KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)

Discover Target: KDM4A

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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

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SNCA Tchem Alpha-synuclein (10960 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)

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GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

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microRNA 21 (64692 Activities)

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CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

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BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)

Discover Target: BAZ2B

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ATXN2 Tbio Ataxin-2 (54410 Activities)

Discover Target: ATXN2

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RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)

Discover Target: RGS4

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)

Discover Target: IDH1

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RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 Activities)

Discover Target: RAPGEF4

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GSK3A Tclin Glycogen synthase kinase-3 (736 Activities)

Discover Target: GSK3A

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Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

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Nannizzia gypsea (2039 Activities)

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Aspergillus flavus (8875 Activities)

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Aspergillus niger (16508 Activities)

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Saccharomyces cerevisiae (19171 Activities)

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Pichia kudriavzevii (7448 Activities)

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Kluyveromyces marxianus (909 Activities)

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Aspergillus fumigatus (16427 Activities)

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Plasmodium falciparum (966862 Activities)

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Cryptococcus neoformans (21258 Activities)

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Candida albicans (78123 Activities)

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Nakaseomyces glabratus (9108 Activities)

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Candida parapsilosis (8521 Activities)

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Candida tropicalis (8381 Activities)

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Trichophyton rubrum (3646 Activities)

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Plasmodium berghei (192651 Activities)

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Clavispora lusitaniae (671 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

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ddn Putative uncharacterized protein (49 Activities)

Discover Target: ddn

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Trichophyton mentagrophytes (4846 Activities)

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TGR Thioredoxin glutathione reductase (28579 Activities)

Discover Target: TGR

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

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ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

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NS1 Nonstructural protein 1 (33327 Activities)

Discover Target: NS1

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vpr Aberrant vpr protein (14595 Activities)

Discover Target: vpr

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Mechanisms of Action

Chemical and Physical Properties

• Boil Point(°C): 177 °C/20 mmHg
• Melt Point(°C): 70 °C
• Molecular Weight: 187.190 g/mol
• XLogP3: 1.000
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 187.063 Da
• Monoisotopic Mass: 187.063 Da
• Topological Polar Surface Area: 37.400 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 259.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Xu Yang, Maosheng Lin, Jirui Wei, Jing Sun.  (2022)  A self-crosslinking nanogel scaffold for enhanced catalytic efficiency and stability.  Polymer Chemistry,  14  (3): (284-294).  [PMID:] [10.1039/D2PY01272C]

2. Chi Lei, Qixiu Weng, Ping Song, Yingchun Zhu, Liangzhi Li, Lingzhao Kong, Lishi Yan.  (2026)  Thiol Modification of β-Glucosidase via N-Methoxycarbonylmaleimide for Enhancement of Catalytic Efficiency and Environmental Tolerance.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:41703775] [10.1021/acs.jafc.5c17409]