N-Benzylpalmitamide - Moligand™,≥98% , CAS No.74058-71-2

CAS: 74058-71-2 Cat. No.: N649447 Molecular Weight: 345.56 PubChem CID: 11198769

GRADE & PURITY Moligand™, ≥98%

Synonyms

MacamideB | MLGPKWUKOQAAGI-UHFFFAOYSA-N | CHEBI:140849 | FT-0775820 | BDBM50438776 | MS-25310 | N-Benzylhexadecanamide;Macamide 1 | HY-N2365 | Macamide 1 | UNII-1M5UVS8JUU | Macamide B | N-Benzyl Hexadecanamide | AC-34557 | DTXSID50458532 | LMFA08020155 |

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii , acts as an inhibitor of fatty acid amide hydrolase (FAAH) .

In Vitro

N-Benzylpalmitamide is an inhibitor of fatty acid amide hydrolase (FAAH), and shows 24.8% and 43.8% inhibition on FAAH at 10 μM and 500 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:FAAH

Specifications

Synonyms

MacamideB | MLGPKWUKOQAAGI-UHFFFAOYSA-N | CHEBI:140849 | FT-0775820 | BDBM50438776 | MS-25310 | N-Benzylhexadecanamide;Macamide 1 | HY-N2365 | Macamide 1 | UNII-1M5UVS8JUU | Macamide B | N-Benzyl Hexadecanamide | AC-34557 | DTXSID50458532 | LMFA08020155 |

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii , acts as an inhibitor of fatty acid amide hydrolase (FAAH) .

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CCCCCCCCCCCCCCCC(=O)NCC1=CC=CC=C1
• IUPAC Name: N-benzylhexadecanamide
• InChIKey: MLGPKWUKOQAAGI-UHFFFAOYSA-N
• INCHI: 1S/C23H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-23(25)24-21-22-18-15-14-16-19-22/h14-16,18-19H,2-13,17,20-21H2,1H3,(H,24,25)
• Isomeric SMILES: CCCCCCCCCCCCCCCC(=O)NCC1=CC=CC=C1
• Alternate CAS: 74058-71-2
• PubChem CID: 11198769
• MeSH Entry Terms: N-benzylhexadecanamide
• Molecular Weight: 345.56

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Fatty Acyls
      • Subclass Fatty amides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Fatty Acyls
• Subclass: Fatty amides
• Intermediate Tree Nodes: Not available
• Direct Parent: N-acyl amines
• Alternative Parents: Benzene and substituted derivatives Secondary carboxylic acid amides Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzenoid - N-acyl-amine - Monocyclic benzene moiety - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as n-acyl amines. These are compounds containing a fatty acid moiety linked to an amine group through an ester linkage.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

EPHX2 Tchem Bifunctional epoxide hydrolase 2 (1 Activities)

Discover Target: EPHX2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EPHX2 Tchem Epoxide hydratase (3844 Activities)

Discover Target: EPHX2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

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THP-1 (11052 Activities)

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U-251 (51189 Activities)

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786-0 (47912 Activities)

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NCI/ADR-RES (33767 Activities)

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HaCaT (4069 Activities)

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NCI-H460 (60772 Activities)

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Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: DMSO : 2.5 mg/mL (7.23 mM; ultrasonic and warming and heat to 60°C)
• Sensitivity: light sensitive；Moisture sensitive
• Molecular Weight: 345.600 g/mol
• XLogP3: 8.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 16
• Exact Mass: 345.303 Da
• Monoisotopic Mass: 345.303 Da
• Topological Polar Surface Area: 29.100 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 296.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1