NBD C6 ceramide , CAS No.86701-10-2

CAS: 86701-10-2 Cat. No.: N598331 Molecular Weight: 575.74

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product introduction：

NBD C6 ceramide is a fluorescent sphingolipid analog that can be used to study sphingolipid transport and metabolic mechanisms. It can also be used to selectively stain the Golgi apparatus in living and fixed cells. The environmentally sensitive NBD dye emits weak fluorescence in water, but the fluorescence increases in aprotic solvents and other nonpolar environments.

Product parameters：

Appearance: Orange solid soluble in dichloromethane, methanol, DMSO or DMF ex/em:466/530 nm (in MeOH) molecular formula: c30h49n5o6 molecular weight: 575.7cas No.: 86701-10-2

Matters needing attention：

1. fluorescent dyes have quenching problems. Please try to avoid light to slow down fluorescence quenching. 2. if the suspended cells are stained for Golgi, it is recommended to stain at 2x106 cell/ml 3 For your safety and health, please wear lab clothes and disposable gloves.

Scope of application：

Golgi staining

Specifications

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])O
• IUPAC Name: N-[(E)-1,3-dihydroxyoctadec-4-en-2-yl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide
• InChIKey: HZIRBXILQRLFIK-OBGWFSINSA-N
• INCHI: 1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+
• Isomeric SMILES: CCCCCCCCCCCCC/C=C/C(C(CO)NC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])O
• Molecular Weight: 575.74
• Reaxy-Rn: 35291078
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=35291078&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Sphingolipids
      • Subclass Ceramides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Sphingolipids
• Subclass: Ceramides
• Intermediate Tree Nodes: Not available
• Direct Parent: Ceramides
• Alternative Parents: Benzoxadiazoles Nitroaromatic compounds Secondary alkylarylamines N-acyl amines Benzenoids Heteroaromatic compounds Furazans Secondary carboxylic acid amides Secondary alcohols Amino acids and derivatives Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Organic zwitterions Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Ceramide - Benzoxadiazole - Nitroaromatic compound - Secondary aliphatic/aromatic amine - Fatty acyl - Benzenoid - N-acyl-amine - Fatty amide - Heteroaromatic compound - Oxadiazole - Furazan - Azole - Organic nitro compound - Secondary carboxylic acid amide - Secondary alcohol - C-nitro compound - Carboxamide group - Amino acid or derivatives - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Secondary amine - Organic oxoazanium - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic zwitterion - Primary alcohol - Organooxygen compound - Organonitrogen compound - Carbonyl group - Amine - Alcohol - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as ceramides. These are lipid molecules containing a sphingosine in which the amine group is linked to a fatty acid.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in trichloromethane ; Methanol ; DMSO ; DMF