≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor , displays about 20-fold difference in the affinity for high ( K i = 84 nM, M1 receptor) and low ( K i = 1.65 μM, M2 receptor) affinity sites Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment .
Form:Solid
IC50& Target:H 1 Receptor mGluR 1 84 nM (Ki) mGluR2 1.65 μM (Ki)
| Canonical Smiles | CC(CN1C2=CC=CC=C2S(=O)(=O)C3=CC=CC=C31)CN(C)C |
|---|---|
| IUPAC Name | 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine |
| InChIKey | QTQPVLDZQVPLGV-UHFFFAOYSA-N |
| INCHI | 1S/C18H22N2O2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3 |
| Isomeric SMILES | CC(CN1C2=CC=CC=C2S(=O)(=O)C3=CC=CC=C31)CN(C)C |
| PubChem CID | 19396 |
| Molecular Weight | 330.44 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Benzothiazines |
| Subclass | Phenothiazines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenothiazines |
| Alternative Parents | Alkyldiarylamines Benzenoids 1,4-thiazines Sulfones Trialkylamines Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Phenothiazine - Alkyldiarylamine - Tertiary aliphatic/aromatic amine - Para-thiazine - Benzenoid - Sulfone - Tertiary amine - Tertiary aliphatic amine - Azacycle - Amine - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring. |
| External Descriptors | Not available |
| Solubility | DMSO : 100 mg/mL (302.63 mM; Need ultrasonic) |
|---|---|
| Molecular Weight | 330.400 g/mol |
| XLogP3 | 3.400 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 330.14 Da |
| Monoisotopic Mass | 330.14 Da |
| Topological Polar Surface Area | 49.000 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 470.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
