Pal-Gly-Gln-Pro-Arg-OH, CAS No.221227-05-0

CAS: 221227-05-0 Cat. No.: P292761 Molecular Weight: 694.91 PubChem CID: 10078408

GRADE & PURITY ≥98%

Overview

It can delay and inhibit the production of excessive cell interleukin, thereby   inhibiting some unnecessary and inappropriate inflammation and glycosylation damage.

Efficacy and Mechanism of Action

Palmitoyl tetrapeptide-7 (Rigin TM) (sequence: Pal-Gly-Gln-Pro-Arg or pal-GQPR) is a fragment of immunoglobulin G. Palmitoyl tetrapeptide-7 reduces IL-6 secretion in the basic environment and is used as an anti-inflammatory agent after exposure to UVB radiation. In vivo reflection confocal microscopy showed that the mixture of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 enhanced the structure of extracellular matrix compared with placebo.

Specifications

Product Name

Pal-Gly-Gln-Pro-Arg-OH, CAS No.221227-05-0

Synonyms

PALMITOYL TETRAPEPTIDE-7 [INCI] | l-Arginine, N-(1-oxohexadecyl)glycyl-l-glutaminyl-l-prolyl- | Palmitoyl-GQPR | HY-P0064 | MFCD11977710 | Pal-Gly-Gln-Pro-Arg-OH | Palmitoyl Tetrapeptide-3 | (S)-2-[(S)-1-[(S)-5-Amino-5-oxo-2-(2-palmitamidoacetamido)pentan

Specifications & Purity

≥98%

Sequence

Pal-Gly-Gln-Pro-Arg

Action Type

INHIBITOR

CAS

221227-05-0

Molecule Type

Peptide

Storage and Shipping

Storage

Store at 2-8°C

Shipped In

Wet ice

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Proline and derivatives N-acyl-L-alpha-amino acids Alpha amino acid amides Pyrrolidinecarboxamides N-acylpyrrolidines Heterocyclic fatty acids N-acyl amines Tertiary carboxylic acid amides Secondary carboxylic acid amides Guanidines Primary carboxylic acid amides Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Carboxylic acids Carboximidamides Monocarboxylic acids and derivatives Hydrocarbon derivatives Carbonyl compounds Organic oxides
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Alpha-oligopeptide - Proline or derivatives - N-acyl-alpha-amino acid - N-acyl-l-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - N-acylpyrrolidine - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - Heterocyclic fatty acid - Fatty amide - Fatty acid - N-acyl-amine - Fatty acyl - Tertiary carboxylic acid amide - Pyrrolidine - Carboxamide group - Secondary carboxylic acid amide - Guanidine - Primary carboxylic acid amide - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboxylic acid - Carboximidamide - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Azacycle - Organic oxide - Carbonyl group - Organic nitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Organonitrogen compound - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y