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· · COA & SDS available for every product · Same-day shipping on in-stock items PF-4708671 - Moligand™, ≥98% , Inhibitor of ribosomal protein S6 kinase B1, CAS No.1255517-76-0, Inhibitor of ribosomal protein S6 kinase B1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
AKOS024457939 | BCP07961 | MFCD18086922 | HY-15773 | CCG-222583 | Prestwick2_001094 | FBLPQCAQRNSVHB-UHFFFAOYSA-N | D0178 | J-015549 | 2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole | 2-[[4-(5-ethylpyrimidin-4
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
AKOS024457939 | BCP07961 | MFCD18086922 | HY-15773 | CCG-222583 | Prestwick2_001094 | FBLPQCAQRNSVHB-UHFFFAOYSA-N | D0178 | J-015549 | 2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole | 2-[[4-(5-ethylpyrimidin-4
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) (Ki= 20 nM; IC50= 160 nM). Suppresses the S6K1-mediated phosphorylation of S6, Rictor and mTOR in response to IGF1; displays no effect on the activity of RSK and MSKin vivo. Exhibits no si
Legal Information
Sold for only research purposes
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Inhibitor of ribosomal protein S6 kinase B1
Names and Identifiers Pubchem Sid 504771059 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504771059 Canonical Smiles CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F IUPAC Name 2-[[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-1H-benzimidazole InChIKey FBLPQCAQRNSVHB-UHFFFAOYSA-N INCHI 1S/C19H21F3N6/c1-2-13-10-23-12-24-18(13)28-7-5-27(6-8-28)11-17-25-15-4-3-14(19(20,21)22)9-16(15)26-17/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,25,26) Isomeric SMILES CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F WGK Germany 3 Molecular Weight 390.41 Reaxy-Rn 29423278 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29423278&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Diazinanes Subclass Piperazines Intermediate Tree Nodes Not available Direct Parent N-arylpiperazines Alternative Parents Benzimidazoles Dialkylarylamines N-alkylpiperazines Aralkylamines Aminopyrimidines and derivatives Imidolactams Benzenoids Imidazoles Heteroaromatic compounds Trialkylamines Azacyclic compounds Organofluorides Hydrocarbon derivatives Alkyl fluorides Molecular Framework Aromatic heteropolycyclic compounds Substituents N-arylpiperazine - Benzimidazole - Dialkylarylamine - Aminopyrimidine - N-alkylpiperazine - Aralkylamine - Imidolactam - Benzenoid - Pyrimidine - Heteroaromatic compound - Azole - Imidazole - Tertiary aliphatic amine - Tertiary amine - Azacycle - Hydrocarbon derivative - Organohalogen compound - Organofluoride - Organic nitrogen compound - Organonitrogen compound - Alkyl fluoride - Amine - Alkyl halide - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as n-arylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an aryl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 19.52, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 19.52, Max Conc. mM: 50 Molecular Weight 390.400 g/mol XLogP3 3.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 8 Rotatable Bond Count 4 Exact Mass 390.178 Da Monoisotopic Mass 390.178 Da Topological Polar Surface Area 60.900 Ų Heavy Atom Count 28 Formal Charge 0 Complexity 510.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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