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· · COA & SDS available for every product · Same-day shipping on in-stock items PF 915275 - ≥98%(HPLC) , CAS No.857290-04-1
Synonyms
PF-915275; PF915275 | PF-915275 | SCHEMBL4384483 | BDBM29864 | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide | BCP28049 | 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide | EC-000.2428 | N-(Pyridin-2-yl) arylsulfonamide, 26
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
PF-915275; PF915275 | PF-915275 | SCHEMBL4384483 | BDBM29864 | N-(6-Amino-2-pyridinyl)-4'-cyano-[1, 1'-biphenyl]-4-sulfonamide | BCP28049 | 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide | EC-000.2428 | N-(Pyridin-2-yl) arylsulfonamide, 26
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki= 2.3 nM) that displays little activity at 11βHSD2 (1.5% inhibition at 10μM). Inhibits the conversion of prednisone to prednisolone in human hepatocytesin vitro(EC50= 15 n
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N IUPAC Name N-(6-aminopyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide InChIKey ZESFDAKNYJQYKO-UHFFFAOYSA-N INCHI 1S/C18H14N4O2S/c19-12-13-4-6-14(7-5-13)15-8-10-16(11-9-15)25(23,24)22-18-3-1-2-17(20)21-18/h1-11H,(H3,20,21,22) Isomeric SMILES C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N PubChem CID 23725123 Molecular Weight 350.39
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Biphenyls and derivatives Intermediate Tree Nodes Not available Direct Parent Biphenylcarbonitriles Alternative Parents Benzenesulfonamides Benzenesulfonyl compounds Benzonitriles Aminopyridines and derivatives Organosulfonamides Imidolactams Heteroaromatic compounds Aminosulfonyl compounds Nitriles Azacyclic compounds Primary amines Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Biphenylcarbonitrile - Benzenesulfonamide - Benzenesulfonyl group - Benzonitrile - Aminopyridine - Pyridine - Imidolactam - Organosulfonic acid amide - Heteroaromatic compound - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Aminosulfonyl compound - Sulfonyl - Carbonitrile - Nitrile - Azacycle - Organoheterocyclic compound - Organosulfur compound - Organonitrogen compound - Organic nitrogen compound - Amine - Organic oxide - Cyanide - Primary amine - Hydrocarbon derivative - Organic oxygen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as biphenylcarbonitriles. These are organic compounds containing an acetonitrile with one hydrogen replaced by a biphenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 35.04, Max Conc. mM: 100 Molecular Weight 350.400 g/mol XLogP3 2.700 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 350.084 Da Monoisotopic Mass 350.084 Da Topological Polar Surface Area 117.000 Ų Heavy Atom Count 25 Formal Charge 0 Complexity 578.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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