average Mw ~50,000, PDI 3‑4 for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Application
This Poly(2-ethyl-2-oxazoline) polymer is amorphous and water soluble with good temperature stability. Jordan and coworkers showed biocompatibility, no accumulation in tissue, and rapid clearance from the bloodstream. End-group modified poly(2-ethyl-2-oxazoline)s have been conjugated to peptides, and were shown as versatile alternatives to poly(ethylene glycol) (PEG) for both protein and small drug conjugation. Potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone). Adhesion promoter in coatings. Heat sealing and remoistenable hot-melt adhesive
softening point 110-120 °C (Vicat, ASTM D 1525-82)
Tg 69-71 °C
| Canonical Smiles | CCC1=NCCO1 |
|---|---|
| IUPAC Name | 2-ethyl-4,5-dihydro-1,3-oxazole |
| InChIKey | NYEZZYQZRQDLEH-UHFFFAOYSA-N |
| INCHI | 1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3 |
| Isomeric SMILES | CCC1=NCCO1 |
| Reaxy-Rn | 105464 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=105464&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Azolines |
| Subclass | Oxazolines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Oxazolines |
| Alternative Parents | Imidoesters Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Oxazoline - Imido ester - Oxacycle - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as oxazolines. These are organic compounds containing 1,3-oxazoline, a five-membered ring with a nitrogen and an oxygen atoms at the 1- and 3-position, respectively. Additionally, it contains two double bonds. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2321538 | Certificate of Analysis | Jan 19, 2026 | P432473 |
| C2321676 | Certificate of Analysis | Jan 19, 2026 | P432473 |
| J2524672 | Certificate of Analysis | Jun 09, 2025 | P432473 |
| J2524673 | Certificate of Analysis | Jun 09, 2025 | P432473 |
| I2501614 | Certificate of Analysis | Mar 25, 2025 | P432473 |
| I2501615 | Certificate of Analysis | Mar 25, 2025 | P432473 |
| C2512551 | Certificate of Analysis | Sep 28, 2024 | P432473 |
| C2512552 | Certificate of Analysis | Sep 28, 2024 | P432473 |
| C2405143 | Certificate of Analysis | Feb 18, 2024 | P432473 |
| C2405144 | Certificate of Analysis | Feb 18, 2024 | P432473 |
| C2405145 | Certificate of Analysis | Feb 18, 2024 | P432473 |
| I2311125 | Certificate of Analysis | Aug 23, 2023 | P432473 |
| I2311736 | Certificate of Analysis | Aug 23, 2023 | P432473 |
| C2321532 | Certificate of Analysis | Mar 14, 2023 | P432473 |
| C2321536 | Certificate of Analysis | Mar 14, 2023 | P432473 |
| Solubility | Soluble in water and organic solvents. |
|---|---|
| Sensitivity | Moisture sensitive |
| Refractive Index | 1.52 |
| Molecular Weight | 99.130 g/mol |
| XLogP3 | 0.300 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 99.0684 Da |
| Monoisotopic Mass | 99.0684 Da |
| Topological Polar Surface Area | 21.600 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 88.100 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Cai Chunqi, Chen Qingqing, Su Hongyan, Huang Pengcheng, Mao Junjie, Wu Fang-Ying. (2023) Single copper sites dispersed on metal-organic frameworks boost the degradation of nerve agent simulants. Science China-Materials, 66 (6): (2475-2482). [PMID:] [10.1007/s40843-022-2378-8] |
| 2. Wenyuan Lang, Wanting Zhang, Nuojin Zhang, Hao Huang, Feng Lin, Aimin Ge, Bing Xue, Shuguang Yang. (2025) Effects of pH and Salt Concentration on Assembly and Disassembly of the PEOX-EI-50/PAA Complex Containing Hydrogen Bonding and Electrostatic Force Dual Interaction. MACROMOLECULES, [PMID:] [10.1021/acs.macromol.4c03103] |
