PROTAC KRAS G12C degrader-1 - ≥99% , CAS No.P659476

CAS: P659476 Cat. No.: P659476 Molecular Weight: 917.47
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Application
PROTAC
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
P659476-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$2,560.90
10mg
P659476-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$4,100.90
100mg
P659476-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$21,760.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

PROTAC KRAS G12C degrader-1 is a Cereblon -based KRAS G12C PROTAC degrader. PROTAC KRAS G12C degrader-1 induces CRBN/ KRAS G12C dimerization and degrades GFP- KRAS G12C in reporter cells.

Appearance:Solid

In Vitro:PROTAC KRAS G12C degrader-1 (Compound 10) engages CRBN in cells, bound KRASG12C in vitro, induces CRBN/KRASG12C dimerization, and degrades GFP-KRASG12C in reporter cells in a CRBN-dependent manner. MCE has not independently confirmed the accuracy of

Biological Activity:PROTAC KRAS G12C degrader-1 is a Cereblon -based KRAS G12C PROTAC degrader. PROTAC KRAS G12C degrader-1 induces CRBN/ KRAS G12C dimerization and degrades GFP- KRAS G12C in reporter cells.

Specifications

Specifications & Purity
≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
Molecular Weight 917.47

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilityDMSO : 100 mg/mL (109.00 mM; Need ultrasonic)
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

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