Recombinant Human DNMT3A Protein

Cat. No.: rp218433
AVAILABLE TO ORDER
GRADE & PURITY Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE) See COA
Accession #
Q9Y6K1
Protein Tag
N-His
Expression system
E. coli
Endotoxin Concentration
<1.0 EU/μg
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10μg
rp218433-10μg
3
$279.90
50μg
rp218433-50μg
3
$799.90
100μg
rp218433-100μg
3
$1,199.90
1mg
rp218433-1mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$5,999.90
Enter a quantity for the sizes you want to add.
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Why this grade

Carrier Free,His-Tag,≥95%(SDS-PAGE),See COA Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
Recombinant Human DNMT3A Protein
Synonyms
DNA (cytosine 5) methyltransferase 3 alpha | DNA (cytosine 5) methyltransferase 3A | DNA (cytosine-5)-methyltransferase 3A | DNA cytosine methyltransferase 3A2 | DNA methyltransferase 3 alpha | DNA methyltransferase 3a | DNA methyltransferase HsaIIIA | DN
Grade
Carrier Free, His Tag
Specifications & Purity
Carrier Free, His-Tag, ≥95%(SDS-PAGE), See COA
Biochemical and Physiological Mechanisms
Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates
Endotoxin Concentration
<1.0 EU/μg
Amino Acids
353-486 aa
Sequence
MHHHHHHAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQK
Accession #
Predicted molecular weight
16.2 kDa
SDS-PAGE
20.2 kDa, under reducing conditions; 20.3 & 43.5 kDa, under non-reducing conditions.
Molecule Type
Protein
Storage and Shipping
Concentration
See COA
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ for 12 months. Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Recombinant Human DNMT3A Protein (rp218433) - SDS-PAGE
3 μg/lane of Recombinant Human DNMT3A Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 20.2 kDa under reducing conditions and 20.3 & 43.5 kDa under non-reducing conditions.
Heterotetramer composed of 1 DNMT3A homodimer and 2 DNMT3L subunits (DNMT3L-DNMT3A-DNMT3A-DNMT3L) (PubMed:17713477, PubMed:19834512).

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ25F0724340Certificate of AnalysisMay 20, 2026 rp218433
ZJ25F0724341Certificate of AnalysisMay 20, 2026 rp218433
ZJ25F0724342Certificate of AnalysisMay 20, 2026 rp218433
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Carrier Free grade guide → View His Tag grade guide →

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