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Moligand™, analytical standard, ≥98%(HPLC), for food analysis Analytical standard,Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 17 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Canonical Smiles | CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC |
|---|---|
| IUPAC Name | (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,31-dodecaene |
| InChIKey | WVTKBKWTSCPRNU-KYJUHHDHSA-N |
| INCHI | 1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1 |
| Isomeric SMILES | CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC |
| WGK Germany | 3 |
| RTECS | XE9350000 |
| Molecular Weight | 622.75 |
| Beilstein | 877811 |
| Reaxy-Rn | 79005 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=79005&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lignans, neolignans and related compounds |
| Class | Not available |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Lignans, neolignans and related compounds |
| Alternative Parents | Diarylethers Tetrahydroisoquinolines Anisoles Aralkylamines Alkyl aryl ethers Trialkylamines Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Oxyneolignan skeleton - Diaryl ether - Tetrahydroisoquinoline - Anisole - Alkyl aryl ether - Aralkylamine - Benzenoid - Tertiary amine - Tertiary aliphatic amine - Ether - Oxacycle - Azacycle - Organoheterocyclic compound - Organonitrogen compound - Hydrocarbon derivative - Organic nitrogen compound - Organopnictogen compound - Organooxygen compound - Amine - Organic oxygen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as lignans, neolignans and related compounds. These are plant products of low molecular weight formed primarily from oxidative coupling of two p-propylphenol moieties. They can also be described as micromolecules with two phenylpropanoid units coupled together. They can be attached in various manners, like C5-C5', C8-C8'. Most known natural lignans are oxidized at C9 and C9´ and, based upon the way in which oxygen is incorporated into the skeleton and on the cyclization patterns, a wide range of lignans of very different structural types can be formed. |
| External Descriptors | Isoquinoline alkaloids |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jan 15, 2025 | T107322 | |
| Certificate of Analysis | Jan 15, 2025 | T107322 | |
| Certificate of Analysis | Jan 15, 2025 | T107322 | |
| Certificate of Analysis | Jan 15, 2025 | T107322 | |
| Certificate of Analysis | Jan 15, 2025 | T107322 | |
| Certificate of Analysis | Jan 15, 2025 | T107322 | |
| Certificate of Analysis | Jun 27, 2024 | T107322 | |
| Certificate of Analysis | Jun 27, 2024 | T107322 | |
| Certificate of Analysis | Aug 02, 2023 | T107322 | |
| Certificate of Analysis | Aug 02, 2023 | T107322 | |
| Certificate of Analysis | Aug 02, 2023 | T107322 | |
| Certificate of Analysis | Aug 02, 2023 | T107322 | |
| Certificate of Analysis | Feb 10, 2023 | T107322 | |
| Certificate of Analysis | Jan 26, 2022 | T107322 |
| Melt Point(°C) | 219-222°C |
|---|---|
| Molecular Weight | 622.700 g/mol |
| XLogP3 | 6.400 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 622.304 Da |
| Monoisotopic Mass | 622.304 Da |
| Topological Polar Surface Area | 61.900 Ų |
| Heavy Atom Count | 46 |
| Formal Charge | 0 |
| Complexity | 979.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Wenqian Shang, Jing Zhang, Haibo Song, Shunfei Zhu, Aimin Zhang, Yushuang Hua, Shujun Han, Yan Fu. (2021) Mechanism of Tetrandrine Against Endometrial Cancer Based on Network Pharmacology. Drug Design Development and Therapy, [PMID:34262258] [10.2147/DDDT.S307670] |
| 2. Zhou Yufeng, Duan Liguang, Huang Yixin, Liu Yaqi, Wang Lijuan, Qiao Xiaoqiang. (2021) Ionic Liquid 1-Vinyl-3-dodecylimidazole Bromide Embedded Hybrid Monolithic Column and Its Versatile Post-modification with Amino Acids. Journal of Analysis and Testing, 5 (4): (387-395). [PMID:] [10.1007/s41664-021-00171-2] |
| 3. Liu Mingyang, Du Xuejun, Xu Ke, Yan Binwei, Fan Zaibi, Gao Zideng, Ren Xueqin. (2021) A cationic quantum dot-based ratiometric fluorescent probe to visually detect berberine hydrochloride in human blood serums. Journal of Analytical Science and Technology, 12 (1): (1-9). [PMID:] [10.1186/s40543-021-00261-x] |
| 4. Qing Wang, Ling Tong, Lin Yao, Peng Zhang, Li Xu. (2016) Fingerprinting of traditional Chinese medicines on the C18-Diol mixed-mode column in online or offline two-dimensional liquid chromatography on the single column modes. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:27031576] [10.1016/j.jpba.2016.03.033] |
| 5. Qing Wang, Yao Long, Lin Yao, Li Xu, Zhi-Guo Shi, Lanying Xu. (2015) Preparation, characterization and application of a reversed phase liquid chromatography/hydrophilic interaction chromatography mixed-mode C18-DTT stationary phase. TALANTA, [PMID:26695288] [10.1016/j.talanta.2015.09.009] |
| 6. Qing Wang, Zhi-Yuan Luo, Mao Ye, Yu-Zhuo Wang, Li Xu, Zhi-guo Shi, Lanying Xu. (2015) Preparation, chromatographic evaluation and application of adenosine 5′-monophosphate modified ZrO2/SiO2 stationary phase in hydrophilic interaction chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:25627970] [10.1016/j.chroma.2015.01.017] |
| 7. Zhisheng Xie, Xinjun Xu, Chunyan Xie, Zhikun Liang, Mei Yang, Jieyun Huang, Depo Yang. (2014) PREPARATIVE ISOLATION OF TETRANDRINE AND FANGCHINOLINE FROM RADIX STEPHANIA TETRANDRA USING REVERSED-PHASE FLASH CHROMATOGRAPHY. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, [PMID:] [10.1080/10826076.2012.745139] |
| 8. Ruan Lin, Huang Huan-Sen, Jin Wen-Xiang, Chen Hai-Ming, Li Xiong-Juan, Gong Qing-Juan. (2013) Tetrandrine Attenuated Cerebral Ischemia/Reperfusion Injury and Induced Differential Proteomic Changes in a MCAO Mice Model Using 2-D DIGE. NEUROCHEMICAL RESEARCH, 38 (9): (1871-1879). [PMID:23780673] [10.1007/s11064-013-1093-1] |
| 9. Lihong Liu, Shenglan Li, Zilin Chen. (2011) Simultaneous determination of tetrandrine and fangchinoline in herbal medicine Stephania tetrandra S. Moore by liquid chromatography with electrochemical detection. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:22196802] [10.1016/j.jpba.2011.11.027] |
| 10. Yunyan Chen, Ziwei Zhang, Zhilei Qian, Rui Ma, Minna Luan, Yu Sun. (2024) Sequentially Released Liposomes Enhance Anti-Liver Cancer Efficacy of Tetrandrine and Celastrol-Loaded Coix Seed Oil. International Journal of Nanomedicine, [PMID:38288265] [10.2147/IJN.S446895] |
| 11. Yan Li, Shuai Wang, Fang Xiang Song, Li Zhang, Wei Yang, Hong Xia Wang, Qian Lin Chen. (2020) A pH-sensitive drug delivery system based on folic acid-targeted HBP-modified mesoporous silica nanoparticles for cancer therapy. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2020.124470] |
| 12. Qing Wang, Jie Chen, Kun Huang, Xin Zhang, Li Xu, Zhi-guo Shi. (2014) Preparation, characterization and application of N-methylene phosphonic acid chitosan grafted magnesia–zirconia stationary phase. ANALYTICA CHIMICA ACTA, [PMID:25479884] [10.1016/j.aca.2014.11.022] |
| 13. Liyun Ma, Si-Min Liu, Lin Yao, Li Xu. (2014) Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica. JOURNAL OF CHROMATOGRAPHY A, [PMID:25528071] [10.1016/j.chroma.2014.12.002] |
| 14. Xinyan Chen, Xiao Yu, Hao Feng, Panpan Shang, Muhammad Shafiq, Zhengchao Yuan, Cheng Li, Zewen Wang, Zhenchao Liu, Yuan Yao, Mohamed EL-Newehy, Meera Moydeen Abdulhameed, Yan Xiong, Yuan Xu, Xiumei Mo. (2025) Tetrandrine-loaded electrospun scaffold modulates inflammation and fibroblast activity to promote tendon regeneration. Applied Materials Today, [PMID:] [10.1016/j.apmt.2025.102723] |
| 15. Yifan Peng, Xiaoqin Cai, Shanshan Wang, Kaikun Pi, Bin Sun, Yan Li, Bing Liu, Fangxiang Song. (2025) Anisotropic Growth Method for Constructing Stimulus-Responsive Janus Composite Nanoparticles for Dual-Drug Delivery in Tumor Therapy. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:41317457] [10.1016/j.colsurfb.2025.115301] |
| 16. Yue Zhang, Xi Liu, Li Hu, Tengyun Zuo, Kun Xia, Hao Wang, Huaming Yang. (2026) Inorganic–Organic Interfacial Engineering of Earth-Abundant Phytoliths for Multifunctional Hemostat. ACS Applied Bio Materials, [PMID:41563372] [10.1021/acsabm.5c02277] |
| 17. Huanhuan Zhu, Yong Xu, Jiafen Huang, Yiheng Zhang, Manman Sun, Zhiming Wang, Yurong Wang. (2026) Multimodal Voltammetric sensor using Pd@ErGO nanocomposite for selective or simultaneous determination of Tetrandrine and Fangchinoline in traditional Chinese medicine and biological matrices. Results in Chemistry, [PMID:] [10.1016/j.rechem.2026.103274] |
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