SRT 1460 - ≥98% , CAS No.925432-73-1
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SKU
S334321
a drug in development intendede as a small-molecule activator of sirtuin subtype SIRT1.
SRT 1460 is a drug in development intendede as a small-molecule activator of sirtuin subtype SIRT1. SRT 1460 shows positive selectivity of SIRT1 versus SIRT2 and SIRT3. In animal studies, SRT 1460 was shown to have similar activity to resveratrol, a known SIRT1 activator. SRT 1460, however, is closer in potency to SRT 1720 than it is to resveratrol. SRT 1460 was observed in animal studies improving insulin sensitivity, lowering plasma glucose levels, and increasing metabolic function in mitochondria.
More Information
| CAS | 925432-73-1 |
|---|---|
| Synonyms | BRD-K20979596-019-01-6 | MFCD19053214 | SCHEMBL1302286 | 3,4,5-Trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide | 3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide | 3,4,5-TRIME |
| Specifications & Purity | ≥98% |
| Storage | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | SRT 1460 is a drug in development intendede as a small-molecule activator of sirtuin subtype SIRT1. SRT 1460 shows positive selectivity of SIRT1 versus SIRT2 and SIRT3. In animal studies, SRT 1460 was shown to have similar activity to resveratrol, a known SIRT1 activator. SRT 1460, however, is closer in potency to SRT 1720 than it is to resveratrol. SRT 1460 was observed in animal studies improving insulin sensitivity, lowering plasma glucose levels, and increasing metabolic function in mitochondria. |
| Pubchem Sid | 504769734 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504769734 |
| PubChem CID | 24180124 |
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