YK 3-237 - ≥98%(HPLC) , CAS No.1215281-19-8

Name: YK 3-237 - ≥98%(HPLC) , CAS No.1215281-19-8
Brand: Aladdin Scientific
SKU: Y286860
Availability: InStock

CAS: 1215281-19-8 Cat. No.: Y286860 Molecular Weight: 372.18 PubChem CID: 24881094

COA

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YK 3-237 - ≥98%(HPLC) CAS No(1215281-19-8) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY ≥98%(HPLC)

Synonyms

B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid | B-[2-methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]-boronic acid | YK-3-237

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms

B-[2-Methoxy-5-[(1E)-3-oxo-3-(3, 4, 5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid | B-[2-methoxy-5-[(1E)-3-oxo-3-(3, 4, 5-trimethoxyphenyl)-1-propen-1-yl]phenyl]-boronic acid | YK-3-237

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

SIRT1 activator. Inhibits proliferation of breast cancer cell lines expressing mutant p53. Induces G2/M cell cycle arrest and apoptosis in triple negative breast cancer cells (TNBCs)in vitro.YK-3-237 is an activator of sirtuin-1 (SIRT1). YK-3-237 showed a

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(HPLC)

Names and Identifiers

Canonical Smiles	B(C1=C(C=CC(=C1)C=CC(=O)C2=CC(=C(C(=C2)OC)OC)OC)OC)(O)O
IUPAC Name	[2-methoxy-5-[(E)-3-oxo-3-(3,4,5-trimethoxyphenyl)prop-1-enyl]phenyl]boronic acid
InChIKey	AKNGHUAJAODDJA-FNORWQNLSA-N
INCHI	1S/C19H21BO7/c1-24-16-8-6-12(9-14(16)20(22)23)5-7-15(21)13-10-17(25-2)19(27-4)18(11-13)26-3/h5-11,22-23H,1-4H3/b7-5+
Isomeric SMILES	B(C1=C(C=CC(=C1)/C=C/C(=O)C2=CC(=C(C(=C2)OC)OC)OC)OC)(O)O
PubChem CID	24881094
Molecular Weight	372.18

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Phenylpropanoids and polyketides
  - Class Linear 1,3-diarylpropanoids
    - Subclass Chalcones and dihydrochalcones

Kingdom	Organic compounds
Superclass	Phenylpropanoids and polyketides
Class	Linear 1,3-diarylpropanoids
Subclass	Chalcones and dihydrochalcones
Intermediate Tree Nodes	Not available
Direct Parent	Retrochalcones
Alternative Parents	Cinnamic acids and derivatives Styrenes Phenoxy compounds Methoxybenzenes Benzoyl derivatives Aryl ketones Anisoles Alkyl aryl ethers Enones Acryloyl compounds Boronic acids Organic metalloid salts Organometalloid compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Retrochalcone - Cinnamic acid or derivatives - Phenoxy compound - Anisole - Methoxybenzene - Aryl ketone - Styrene - Phenol ether - Benzoyl - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Acryloyl-group - Alpha,beta-unsaturated ketone - Enone - Boronic acid derivative - Boronic acid - Ketone - Organic metalloid salt - Ether - Organic oxide - Organic oxygen compound - Organooxygen compound - Organic metalloid moeity - Hydrocarbon derivative - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as retrochalcones. These are a form of normal chalcones that are structurally distinguished by the lack of oxygen functionalities at the C2'- and C6'-positions.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

A498 (42825 Activities)

Lot Number	Certificate Type	Date	Item
J2516217	Certificate of Analysis	Oct 27, 2025	Y286860
K2118409	Certificate of Analysis	Sep 20, 2024	Y286860
K2118535	Certificate of Analysis	Sep 20, 2024	Y286860
K2118538	Certificate of Analysis	Sep 20, 2024	Y286860
K2118539	Certificate of Analysis	Sep 20, 2024	Y286860
K2118544	Certificate of Analysis	Sep 20, 2024	Y286860
K2118552	Certificate of Analysis	Sep 20, 2024	Y286860

Solubility	Solvent:DMSO, Max Conc. mg/mL: 37.22, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 37.22, Max Conc. mM: 100
Molecular Weight	372.200 g/mol
XLogP3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	8
Exact Mass	372.138 Da
Monoisotopic Mass	372.138 Da
Topological Polar Surface Area	94.500 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	484.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1