≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Zardaverine is a newly developed dual-selective PDE3/4 inhibitor with IC50 values of 0.5 uM and 0.8 uM respectively.
A pyridazinone derivative and a selective inhibitor of phosphodiesterase type III and IV
| Canonical Smiles | COC1=C(C=CC(=C1)C2=NNC(=O)C=C2)OC(F)F |
|---|---|
| IUPAC Name | 3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one |
| InChIKey | HJMQDJPMQIHLPB-UHFFFAOYSA-N |
| INCHI | 1S/C12H10F2N2O3/c1-18-10-6-7(2-4-9(10)19-12(13)14)8-3-5-11(17)16-15-8/h2-6,12H,1H3,(H,16,17) |
| Isomeric SMILES | COC1=C(C=CC(=C1)C2=NNC(=O)C=C2)OC(F)F |
| PubChem CID | 5723 |
| Molecular Weight | 268.22 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Diazines |
| Subclass | Pyridazines and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylpyridazines |
| Alternative Parents | Phenoxy compounds Methoxybenzenes Anisoles Pyridazinones Alkyl aryl ethers Heteroaromatic compounds Lactams Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Phenylpyridazine - Anisole - Phenol ether - Methoxybenzene - Phenoxy compound - Alkyl aryl ether - Pyridazinone - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Lactam - Azacycle - Ether - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Alkyl fluoride - Alkyl halide - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as phenylpyridazines. These are organic compounds containing a pyridazine ring substituted by a phenyl group. |
| External Descriptors | organofluorine compound - pyridazinone |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2412798 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| J2412799 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| J2412800 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| J2412801 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| J2412802 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| J2412803 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| J2412804 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| J2412805 | Certificate of Analysis | Sep 30, 2024 | Z127987 |
| Solubility | Solvent:DMSO, Max Conc. mg/mL: None, Max Conc. mM: 100 |
|---|---|
| Molecular Weight | 268.220 g/mol |
| XLogP3 | 2.200 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 4 |
| Exact Mass | 268.066 Da |
| Monoisotopic Mass | 268.066 Da |
| Topological Polar Surface Area | 59.900 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 398.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
