≥95%(T) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
10,12-Tricosadiynoic acid is a highly specific, selective, high affinity and acyl-CoA oxidase-1 (ACOX1) inhibitor. 10,12-Tricosadiynoic acid can treat high fat diet- or obesity-induced metabolic diseases by improving mitochondrial lipid and ROS metabolism[1]. 10,12-Tricosadiynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Canonical Smiles | CCCCCCCCCCC#CC#CCCCCCCCCC(=O)O |
|---|---|
| IUPAC Name | tricosa-10,12-diynoic acid |
| InChIKey | DIEDVCMBPCRJFQ-UHFFFAOYSA-N |
| INCHI | 1S/C23H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23(24)25/h2-10,15-22H2,1H3,(H,24,25) |
| Isomeric SMILES | CCCCCCCCCCC#CC#CCCCCCCCCC(=O)O |
| WGK Germany | 3 |
| PubChem CID | 538457 |
| Molecular Weight | 346.56 |
| Beilstein | 1880410 |
| Reaxy-Rn | 1880414 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Fatty Acyls |
| Subclass | Fatty acids and conjugates |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Very long-chain fatty acids |
| Alternative Parents | Unsaturated fatty acids Straight chain fatty acids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Very long-chain fatty acid - Unsaturated fatty acid - Straight chain fatty acid - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as very long-chain fatty acids. These are fatty acids with an aliphatic tail that contains at least 22 carbon atoms. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2403296 | Certificate of Analysis | Mar 13, 2026 | T162085 |
| F2403297 | Certificate of Analysis | Mar 13, 2026 | T162085 |
| F2403314 | Certificate of Analysis | Mar 13, 2026 | T162085 |
| F2403319 | Certificate of Analysis | Mar 13, 2026 | T162085 |
| J2530774 | Certificate of Analysis | Oct 17, 2025 | T162085 |
| J2530775 | Certificate of Analysis | Oct 17, 2025 | T162085 |
| J2530776 | Certificate of Analysis | Oct 17, 2025 | T162085 |
| K2514713 | Certificate of Analysis | Sep 29, 2025 | T162085 |
| K2514714 | Certificate of Analysis | Sep 29, 2025 | T162085 |
| F2403298 | Certificate of Analysis | May 23, 2024 | T162085 |
| F2403317 | Certificate of Analysis | May 23, 2024 | T162085 |
| F2403318 | Certificate of Analysis | May 23, 2024 | T162085 |
| D2312227 | Certificate of Analysis | Feb 07, 2023 | T162085 |
| E2306651 | Certificate of Analysis | Feb 07, 2023 | T162085 |
| F1927192 | Certificate of Analysis | Feb 07, 2023 | T162085 |
| J2222022 | Certificate of Analysis | Nov 10, 2022 | T162085 |
| Solubility | Insoluble in water. |
|---|---|
| Sensitivity | light sensitive，heat sensitive |
| Melt Point(°C) | 55-59°C |
| Molecular Weight | 346.500 g/mol |
| XLogP3 | 8.300 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 17 |
| Exact Mass | 346.287 Da |
| Monoisotopic Mass | 346.287 Da |
| Topological Polar Surface Area | 37.300 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 438.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jiaying Lin, Rulin Liu, Xi Zhu, Alexander Wei, Xiaoqian Xu, Tingchao He, Jiaji Cheng, Yiwen Li. (2022) Chiroptical Transitions of Enantiomeric Ligand-Activated Nickel Oxides. Small, 18 (14): (2107570). [PMID:35187806] [10.1002/smll.202107570] |
| 2. Jiayue Zhou, Dong Li, Yanqun Xu, Xiaochen Zhang, Lei Wang, Lin Zhou, Liang Zou, Zisheng Luo. (2024) Biomolecule-functionalized polydiacetylene assembly for visual and on-site sensing of (E)-2-hexenal in fruits. JOURNAL OF FOOD SCIENCE, 89 (12): (9271-9282). [PMID:39674853] [10.1111/1750-3841.17395] |
| 3. Hongwei Li, Zhibin Liu, Pengju Lei, Jichong Xia, Shoudeng Wang, Guixian Li, Xinhong Zhao, Dong ji. (2025) PEG-400 Assisted Preparation of High-Loading Highly Dispersed Ni/AC Catalyst and Its Hydrogenation Performance for DNT. ChemistrySelect, 10 (37): (e04026). [PMID:] [10.1002/slct.202504026] |
| 4. Mengli Dong, Yu Han, Xinqiang Zhao, Yao Lu, Hualiang An, Yanji Wang. (2026) Nanostructured CeO2 with different morphologies for methoxycarbonylation of 2,4-toluene diamine with dimethyl carbonate. Reaction Chemistry & Engineering, [PMID:] [10.1039/D5RE00469A] |
