1H-Imidazol-2-amine - ≥95% , CAS No.7720-39-0

CAS: 7720-39-0 Cat. No.: H186542 Molecular Weight: 83.1 EC Number: 231-751-4
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
AB07116 | BDBM50316608 | Q27452839 | BBL029017 | STL146908 | BB 0262960 | AL-398/25017027 | FT-0650418 | EN300-27739 | Q-200237 | MFCD00792530 | 1H-Imidazol-2-amine | P10144 | 2-Aminoimidazole, AldrichCPR | PD158409 | EINECS 231-751-4 | SY046108 | AC-051
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
250mg
H186542-250mg
2

$13.90

$20.90
Save $7.00 (33.49%)
1g
H186542-1g
5

$39.90

$59.90
Save $20.00 (33.39%)
5g
H186542-5g
1

$92.90

$139.90
Save $47.00 (33.60%)
Enter a quantity for the sizes you want to add.
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2-Aminoimidazole is a potent antimicrobial agent that effectively targets drug-resistant Mycobacterium tuberculosis by disrupting the proton motive force and blocking the electron transport chain, potentiates the action of beta-lactam antibiotics against Mycobacterium tuberculosis by decreasing the secretion of beta-lactamases and increasing the permeability of cell membranes, activates drug-resistant bacteria and improves therapeutic efficacy.

Specifications

Synonyms
AB07116 | BDBM50316608 | Q27452839 | BBL029017 | STL146908 | BB 0262960 | AL-398/25017027 | FT-0650418 | EN300-27739 | Q-200237 | MFCD00792530 | 1H-Imidazol-2-amine | P10144 | 2-Aminoimidazole, AldrichCPR | PD158409 | EINECS 231-751-4 | SY046108 | AC-051
Specifications & Purity
≥95%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥95%
Names and Identifiers
Pubchem Sid488186057
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488186057
Canonical SmilesC1=CN=C(N1)N
IUPAC Name1H-imidazol-2-amine
InChIKeyDEPDDPLQZYCHOH-UHFFFAOYSA-N
INCHI1S/C3H5N3/c4-3-5-1-2-6-3/h1-2H,(H3,4,5,6)
Isomeric SMILES C1=CN=C(N1)N
Molecular Weight 83.1
Reaxy-Rn 105870
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=105870&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassAzoles
SubclassImidazoles
Intermediate Tree Nodes Substituted imidazoles
Direct ParentAminoimidazoles
Alternative Parents Heteroaromatic compounds  Azacyclic compounds  Primary amines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Aminoimidazole - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as aminoimidazoles. These are organic compounds containing an amino group linked to an imidazole ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NOS1 Tchem Nitric-oxide synthase, brain (1786 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ARG1 Arginase-1 (70 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

20 results found

Lot NumberCertificate TypeDateItem
C2611477Certificate of AnalysisMar 04, 2026 H186542
C2611482Certificate of AnalysisMar 04, 2026 H186542
C2611488Certificate of AnalysisMar 04, 2026 H186542
C2321629Certificate of AnalysisJan 19, 2026 H186542
C2321630Certificate of AnalysisJan 19, 2026 H186542
I2529291Certificate of AnalysisSep 23, 2025 H186542
I2529289Certificate of AnalysisSep 23, 2025 H186542
I2529290Certificate of AnalysisSep 23, 2025 H186542
L2312376Certificate of AnalysisDec 05, 2023 H186542
L2312375Certificate of AnalysisDec 05, 2023 H186542
L2312182Certificate of AnalysisDec 05, 2023 H186542
G2321738Certificate of AnalysisJul 17, 2023 H186542
L2419076Certificate of AnalysisJul 17, 2023 H186542
K2414169Certificate of AnalysisJul 17, 2023 H186542
G2321747Certificate of AnalysisJul 17, 2023 H186542
G2321735Certificate of AnalysisJul 17, 2023 H186542
G2321732Certificate of AnalysisJul 17, 2023 H186542
E2530051Certificate of AnalysisJul 17, 2023 H186542
C2321581Certificate of AnalysisMar 06, 2023 H186542
C2321610Certificate of AnalysisMar 06, 2023 H186542

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Chemical and Physical Properties
Molecular Weight83.090 g/mol
XLogP3-0.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass83.0483 Da
Monoisotopic Mass83.0483 Da
Topological Polar Surface Area54.700 Ų
Heavy Atom Count6
Formal Charge0
Complexity45.300
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Futing Yang, Wenjie Yu, Qiying Yu, Xiyu Liu, Chunping Liu, Chong Lu, Xinghua Liao, Yi Liu, Na Peng.  (2023)  Mitochondria-Targeted Nanosystem with Reactive Oxygen Species-Controlled Release of CO to Enhance Photodynamic Therapy of PCN-224 by Sensitizing Ferroptosis.  Small,  19  (16): (2206124).  [PMID:36693788] [10.1002/smll.202206124]
2. Huan Xu, Mingyue Yang, Yijing Du, Tian Gao, Yi Liu, Liwei Xiong, Na Peng.  (2022)  Self-assembly of micelles with pH/ROS dual-responsiveness and mitochondrial targeting for potential anti-tumor applications.  NEW JOURNAL OF CHEMISTRY,  46  (44): (21235-21244).  [PMID:] [10.1039/D2NJ03244A]
3. Wu Zou, Fuchun Gong, Tingting Gu, Zhong Cao, Jiaoyun Xia.  (2018)  An efficient strategy for sensing pyrophosphate based on nitrogen-rich quantum dots combined with graphene oxide.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2018.06.004]
4. Yujie Guo, Lingfei Li, Maofeng Zhang, Shihao Xu, Changlong Jiang.  (2025)  A Self-Assembly MOF-on-MOF Heterostructure-Driven Fluorescence Sensor for Aerogel-Based Visualization Detection of Flavomycin.  Small,      [PMID:39924837] [10.1002/smll.202410911]
5. Xue Chen, Yong Xiang, Xiaojing Zhang, Guanlin Li, Sihan Ai, Daoyong Yu, Baosheng Ge.  (2024)  Synthesis of a Zn(II)-2-aminoimidazole Framework as an Efficient Carbonic Anhydrase Mimic.  LANGMUIR,      [PMID:39226467] [10.1021/acs.langmuir.4c02563]
6. Yong Xiang, Xue Chen, Liang Zhang, Yu Chen, Xiaowei Peng, Zhongzhen Cai, Qiping Gao, Daoyong Yu, Lu Zhang, Baosheng Ge.  (2026)  Engineering Carbonic Anhydrase Mimics via Metal Ion Doping: Tailoring the Structure and Catalytic Properties of a 2-Aminoimidazole-Based MOF.  LANGMUIR,      [PMID:] [10.1021/acs.langmuir.5c06793]
Solution Calculators
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