Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Standard for GC, ≥99.5%(GC) Standard for GC for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 24 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Canonical Smiles | CC1CCC(C(C1)O)C(C)C |
|---|---|
| IUPAC Name | (1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol |
| InChIKey | NOOLISFMXDJSKH-KXUCPTDWSA-N |
| INCHI | 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1 |
| Isomeric SMILES | C[C@@H]1CC[C@H]([C@@H](C1)O)C(C)C |
| WGK Germany | 2 |
| RTECS | OT0700000 |
| Molecular Weight | 156.27 |
| Beilstein | 1902293 |
| Reaxy-Rn | 1902288 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1902288&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Prenol lipids |
| Subclass | Monoterpenoids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Menthane monoterpenoids |
| Alternative Parents | Monocyclic monoterpenoids Cyclohexanols Cyclic alcohols and derivatives Hydrocarbon derivatives |
| Molecular Framework | Aliphatic homomonocyclic compounds |
| Substituents | P-menthane monoterpenoid - Monocyclic monoterpenoid - Cyclohexanol - Cyclic alcohol - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes. |
| External Descriptors | Menthane monoterpenoids |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jan 20, 2026 | M107058 | |
| Certificate of Analysis | Nov 19, 2025 | M107058 | |
| Certificate of Analysis | Jul 29, 2025 | M107058 | |
| Certificate of Analysis | May 06, 2025 | M107058 | |
| Certificate of Analysis | Aug 21, 2024 | M107058 | |
| Certificate of Analysis | May 10, 2023 | M107058 | |
| Certificate of Analysis | Jun 29, 2021 | M107058 |
| Refractive Index | 1.46 |
|---|---|
| Specific Rotation[α] | -50 ° (C=10, EtOH) |
| Flash Point(°F) | 213.8 °F |
| Flash Point(°C) | 93℃ |
| Boil Point(°C) | 212°C |
| Melt Point(°C) | 41-43°C |
| Molecular Weight | 156.260 g/mol |
| XLogP3 | 3.000 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 156.151 Da |
| Monoisotopic Mass | 156.151 Da |
| Topological Polar Surface Area | 20.200 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 120.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Ang Li, Song Xue, Yu Xu, Sihui Ding, Di Wen, Qi Zhang. (2022) A feasibility study on the use of hydrophobic eutectic solvents as pseudo-stationary phases in capillary electrophoresis for chiral separations. ANALYTICA CHIMICA ACTA, [PMID:36628761] [10.1016/j.aca.2022.340693] |
| 2. Liyu Liu, Zaiyong Zhang, Yinxiang Cheng, Yihua Jiang, Liye Lu, Jian-Rong Wang, Xuefeng Mei. (2022) Stabilizing L-Menthol by Cocrystallization: Supramolecular Cavities Succeeded in Retaining the Volatile Flavor. CRYSTAL GROWTH & DESIGN, [PMID:] [10.1021/acs.cgd.2c00919] |
| 3. Li Yang, Shuang Wang, Zhongshui Xie, Rongrong Xing, Runqin Wang, Xuan Chen, Shuang Hu. (2022) Deep eutectic solvent - loaded Fe3O4@MIL-101(Cr) with core–shell structure for the magnetic solid phase extraction of non-steroidal anti-inflammatory drugs in environmental water samples. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2022.108150] |
| 4. Xinjiao Cui, Donghao Ye, Jiankun Wei, Xiaodi Du, Pengzhao Wang, Junsheng Li. (2022) Controlled Thermal Release of L-Menthol with Cellulose-Acetate-Fiber-Shelled Metal-Organic Framework. MOLECULES, 27 (18): (6013). [PMID:36144758] [10.3390/molecules27186013] |
| 5. Li Liu, Wenna Wu, Xiaoli Chen, Jingcheng Hao, Xingcen Liu, Shuli Dong, Shoutao Cao, Binbin Yao, Hongxiao Yu. (2022) Responsive emulsion gels of glycyrrhizic acid and alanine for cigarette capsules. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2022.129878] |
| 6. Taotao Fan, Zongcheng Yan, Chanyuan Yang, Shunguo Qiu, Xiong Peng, Jianwei Zhang, Lihua Hu, Li Chen. (2021) Preparation of menthol-based hydrophobic deep eutectic solvents for the extraction of triphenylmethane dyes: quantitative properties and extraction mechanism. ANALYST, 146 (6): (1996-2008). [PMID:33507168] [10.1039/D0AN01864C] |
| 7. Xiao-Hong Fan, Li-Tao Wang, Yuan-Hang Chang, Juan-Yan An, Ya-Wei Zhu, Qing Yang, Dong Meng, Yu-jie Fu. (2020) Application of green and recyclable menthol-based hydrophobic deep eutectic solvents aqueous for the extraction of main taxanes from Taxus chinensis needles. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2020.114970] |
| 8. Long Ye, Yichao Lv, Yuanjiang Zhao, Zhuxian Zhou, Youqing Shen, Liming Jiang. (2020) Encapsulation of fragrances in micron-size silk fibroin carriers via coaxial electrohydrodynamic techniques. MATERIALS CHEMISTRY AND PHYSICS, [PMID:] [10.1016/j.matchemphys.2020.124167] |
| 9. Ziman Hu, Songnan Li, Shaokang Wang, Bin Zhang, Qiang Huang. (2020) Encapsulation of menthol into cyclodextrin metal-organic frameworks: Preparation, structure characterization and evaluation of complexing capacity. FOOD CHEMISTRY, [PMID:32822901] [10.1016/j.foodchem.2020.127839] |
| 10. Xiao-Hong Fan, Yuan-Hang Chang, Li-Tao Wang, Ya-Wei Zhu, Ming-Zhu Dong, Mu-Jie Lv, Juan-Yan An, Qing Yang, Jiao Jiao, Dong Meng, Yu-Jie Fu. (2020) A simple and efficient sample preparation for taxanes in Taxus chinensis needles with natural menthol-based aqueous deep eutectic solvent. JOURNAL OF SEPARATION SCIENCE, 43 (7): (1339-1347). [PMID:32017401] [10.1002/jssc.201900754] |
| 11. Changcheng Wu. (2015) Synthesis and Characterization of a Series of Cholesterol-Based Liquid Crystalline Dimers with a Chiral (-)- Menthyl Terminal Group. MOLECULAR CRYSTALS AND LIQUID CRYSTALS, [PMID:] [10.1080/15421406.2014.953759] |
| 12. Qi Tan, Yiwen Liu, Ruifeng An, Heping Wu, Zhiqiang Tian, Bingliang Gao. (2024) DBN-based molecular solvents for highly efficient and reversible CO2 capture. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2024.114470] |
| 13. Jiawei Zhou, Yumin Sang, Zhuang Wang, Jiacheng Feng, Linjiang Zhu, Xiaolong Chen. (2024) Enhancing the Enantioselectivity and Catalytic Efficiency of Esterase from Bacillus subtilis for Kinetic Resolution of l-Menthol through Semirational Design. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:38235660] [10.1021/acs.jafc.3c08321] |
| 14. Bo Yang, Xu Zhang, Liguo Zhang, Jinjin Wu, Wei Wang, Qiaomei Huang, Zhenyuan Wang, Jichuan Zhang, Tongjie Xu, Chengyu Wu, Jiaheng Zhang. (2024) Ionic Liquid-Based Grapeseed Oil Emulsion for Enhanced Anti-Wrinkle Treatment. Pharmaceuticals, 17 (10): (1273). [PMID:39458914] [10.3390/ph17101273] |
| 15. Jiamin Luo, Heng Lu, Bao-Ying Wen, Qiaowen Zheng, Junying Zhang, Yishan Li, Wenping Hong, Shanshan Zhao, Libo Shun, Feiming Li, Zhixiong Cai, Jin-Ming Lin, Qiang Chen, Maosheng Zhang, Jian-Feng Li. (2024) Natural Deep Eutectic Solvents as Absorbing Solution and Preparation Solvent of Perovskite Nanocrystals Simultaneously for CH3I Gas Visual Sensing. ANALYTICAL CHEMISTRY, [PMID:39307967] [10.1021/acs.analchem.4c04776] |
| 16. Jue Chen, Hexiang Zhong, Shan Zhu. (2024) Study on Cu(II) extraction process optimization and mechanism from acidic leaching solution using the deep eutectic solvent P507/Menthol. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2024.123968] |
| 17. Zinuo An, Liangbin Hu, Yuyin Fan, Zhenbin Liu, Hongbo Li, Dan Xu, Lu Tian, Jiayi Zhang, Haizhen Mo. (2025) Thermally-triggered L-menthol release system based on starch sodium octenyl succinate/Nisin-stabilized high internal phase Pickering Emulsion: Development, characterization and meatball coating application. Current Research in Food Science, [PMID:40937070] [10.1016/j.crfs.2025.101187] |
| 18. Zongtao Li, Shaodui Ye, Leshou Zhang, Zhenjuan Duan, Shengchun Yang, Yong Liu, Xiaodong Wen. (2025) Highly sensitive and selective sensing of lead (II) ions in Paris polyphylla using fluorescence-enhanced sulfur quantum dots in deep eutectic solvent micelles. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:40896916] [10.1016/j.saa.2025.126868] |
| 19. Yi Chen, Xuan Wang, Hongyang Ma, Shyam Venkateswaran, Benjamin S. Hsiao. (2025) Chiral electrospun nanofibrous membranes for selective adsorption of chiral compounds. POLYMER, [PMID:] [10.1016/j.polymer.2025.128893] |
| 20. Fuhui Luo, Zhongqiao Zhao, Yong He, Fenfen Zeng, Xia Yang, Fengxiang Zhang, Wei Shi. (2025) A novel pH-switchable deep eutectic solvents system regulated by alkaline/acidic electrolytic water: Efficient extraction of polyphenolic compounds and solvent recycling. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.169349] |
| 21. Danni Lin, Sisi Hu, Leyuan Zhou, Xiaojuan Ma, Lihui Chen, Dong Wang, Liulian Huang. (2025) Enhancing separation and anti-fouling performance of cellulose acetate ultrafiltration membranes by introducing natural deep eutectic solvent. Journal of Water Process Engineering, [PMID:] [10.1016/j.jwpe.2025.109042] |
| 22. Xuejian Zhang, Xiaoke Shi, Hong Xu, Yao Wang, Dikai Zhu, Jianan Liu, Tingting Zhang, Hongqian Shentu, Wei Ding, Jun Lu, Feiyan Tao. (2026) Targeted alleviation of local inflammation by a hydroxypropyl-cyclodextrin-encapsulated prodrug of methyl salicylate and menthol though Nrf2/NF-κB pathway. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:41512796] [10.1016/j.intimp.2026.116171] |
| 23. Xiaotong Lyu, Qi Jiang, Kemin Linghu, Yifei Zhou, Mengqian Yu, Chunhui Wei, Liangcai Lin, Qi Zhou, Zhengshu Zhou, Cuiying Zhang. (2026) Digital transformation of Jiangxiangxing Baijiu production: integrating flavor compound analysis, machine learning recognition, and genetic algorithm blending of multi-rounds. FOOD RESEARCH INTERNATIONAL, [PMID:41794499] [10.1016/j.foodres.2026.118635] |
| 24. Zang Yu, Hou Rui, Wei Bohua, Liu Yuting, Wang Jianjun, Liu Jiao, Xu Liang, Zhang Wei. (2026) Cascade-controlled porous composite membranes: pore-supporting synergy enabling high-flux enantioseparation of amino acids and pharmaceuticals. Science China-Materials, [PMID:] [10.1007/s40843-025-3936-8] |
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