2,2-Bis(3-amino-4-hydroxylphenyl)propane(BAP) - ≥97%(HPLC)(T) , CAS No.1220-78-6

CAS: 1220-78-6 Cat. No.: B152476 Molecular Weight: 258.32 EC Number: 807-962-8

GRADE & PURITY ≥97%(HPLC)(T)

Synonyms

4,4'-Isopropylidenebis(2-aminophenol) | 2,2-bis(3-amino-4-hydroxylphenyl)propane | FT-0651584 | 2,2-Bis(3-amino-4-hydroxylphenyl)propane (BAP) | SR-01000197740 | AC-9177 | 2,2-Bis-(3-amino-4-hydroxyphenyl)propane | 2,2-bis(3-amino-4-hydroxyphenyl)propane

Storage

Room temperature

Shipped In

Normal

Specifications

Synonyms

4, 4'-Isopropylidenebis(2-aminophenol) | 2, 2-bis(3-amino-4-hydroxylphenyl)propane | FT-0651584 | 2, 2-Bis(3-amino-4-hydroxylphenyl)propane (BAP) | SR-01000197740 | AC-9177 | 2, 2-Bis-(3-amino-4-hydroxyphenyl)propane | 2, 2-bis(3-amino-4-hydroxyphenyl)propane

Specifications & Purity

≥97%(HPLC)(T)

Storage

Room temperature

Shipped In

Normal

Purity

≥97%(HPLC)(T)

Names and Identifiers

• Pubchem Sid: 488188727
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488188727
• Canonical Smiles: CC(C)(C1=CC(=C(C=C1)O)N)C2=CC(=C(C=C2)O)N
• IUPAC Name: 2-amino-4-[2-(3-amino-4-hydroxyphenyl)propan-2-yl]phenol
• InChIKey: UHIDYCYNRPVZCK-UHFFFAOYSA-N
• INCHI: 1S/C15H18N2O2/c1-15(2,9-3-5-13(18)11(16)7-9)10-4-6-14(19)12(17)8-10/h3-8,18-19H,16-17H2,1-2H3
• Isomeric SMILES: CC(C)(C1=CC(=C(C=C1)O)N)C2=CC(=C(C=C2)O)N
• Molecular Weight: 258.32
• Reaxy-Rn: 1983742
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1983742&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Bisphenols
• Alternative Parents: Phenylpropanes o-Aminophenols Aniline and substituted anilines 1-hydroxy-2-unsubstituted benzenoids Primary amines Organopnictogen compounds Organooxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Bisphenol - Phenylpropane - Aminophenol - O-aminophenol - Aniline or substituted anilines - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Amine - Primary amine - Hydrocarbon derivative - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as bisphenols. These are methylenediphenols, HOC6H4CH2C6H4OH, commonly p,p-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in Dimethylformamide
• Boil Point(°C): 471°C at 760 mmHg
• Melt Point(°C): 250℃
• Molecular Weight: 258.320 g/mol
• XLogP3: 2.600
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 258.137 Da
• Monoisotopic Mass: 258.137 Da
• Topological Polar Surface Area: 92.500 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 281.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Siyao Wang, Jingfa Zhang, Yongchao Sun, Fangxu Fan, Qizheng Zhao, Gaohong He, Canghai Ma.  (2025)  Thermally rearranged polyimide membranes incorporating triptycenes for improved CO2 capture and hydrogen separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.132302]

2. Shuxin Wang, Hui Li, Gen Zhou, Jingmei Xu, Baoju Li, Xiangzi Wei, Zhe Wang.  (2025)  Bifunctional Sulfonatocalix[4]arene-MOF Fillers Enhance Proton Conductivity of Sulfonated Poly(Arylene Ether Ketone Sulfone) Membranes for Fuel Cells.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.5c07035]