3,3'-Dipropylthiadicarbocyanine iodide - ≥98% , CAS No.53213-94-8

CAS: 53213-94-8 Cat. No.: D131515 Molecular Weight: 546.53 EC Number: 621-258-6 PubChem CID: 5706741
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
DiSC3(5) | AKOS016010215 | HY-D0085 | 3-propyl-2-[(1E,3E)-5-[(2Z)-3-propyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]penta-1,3-dien-1-yl]-1,3-benzothiazol-3-ium iodide | EN300-21687611
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
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Status
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25mg
D131515-25mg
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100mg
D131515-100mg
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250mg
D131515-250mg
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1g
D131515-1g
1

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5g
D131515-5g
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 59 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

3,3'-Dipropylthiadicarbocyanine iodide is applied for transmembrane potential measurements.
Usually used as a fluorogenic probe to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents.

Specifications

Synonyms
DiSC3(5) | AKOS016010215 | HY-D0085 | 3-propyl-2-[(1E, 3E)-5-[(2Z)-3-propyl-2, 3-dihydro-1, 3-benzothiazol-2-ylidene]penta-1, 3-dien-1-yl]-1, 3-benzothiazol-3-ium iodide | EN300-21687611
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Fluorogenic probe used to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents.
Storage
Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Purity
≥98%
Names and Identifiers
Pubchem Sid528757796
Canonical SmilesCCCN1C2=CC=CC=C2SC1=CC=CC=CC3=[N+](C4=CC=CC=C4S3)CCC.[I-]
IUPAC Name(2E)-3-propyl-2-[(2E,4E)-5-(3-propyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-1,3-benzothiazole;iodide
InChIKeyGDEURKKLNUGTDA-UHFFFAOYSA-M
INCHI1S/C25H27N2S2.HI/c1-3-18-26-20-12-8-10-14-22(20)28-24(26)16-6-5-7-17-25-27(19-4-2)21-13-9-11-15-23(21)29-25;/h5-17H,3-4,18-19H2,1-2H3;1H/q+1;/p-1
Isomeric SMILES CCCN\1C2=CC=CC=C2S/C1=C/C=C/C=C/C3=[N+](C4=CC=CC=C4S3)CCC.[I-]
WGK Germany 3
PubChem CID 5706741
Molecular Weight 546.53

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassBenzothiazoles
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzothiazoles
Alternative Parents Benzenoids  Thiazoles  Heteroaromatic compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic iodide salts  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 1,3-benzothiazole - Benzenoid - Heteroaromatic compound - Thiazole - Azole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic iodide salt - Organic salt - Organonitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzothiazoles. These are organic compounds containing a benzene fused to a thiazole ring (a five-membered ring with four carbon atoms, one nitrogen atom and one sulfur atom).
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

27 results found

Lot NumberCertificate TypeDateItem
K2324178Certificate of AnalysisSep 04, 2025 D131515
K2324177Certificate of AnalysisSep 04, 2025 D131515
K2324176Certificate of AnalysisSep 04, 2025 D131515
K2324175Certificate of AnalysisSep 04, 2025 D131515
I2509912Certificate of AnalysisAug 14, 2025 D131515
H2529348Certificate of AnalysisAug 14, 2025 D131515
H2529347Certificate of AnalysisAug 14, 2025 D131515
H2529346Certificate of AnalysisAug 14, 2025 D131515
H2529344Certificate of AnalysisAug 14, 2025 D131515
H2529343Certificate of AnalysisAug 14, 2025 D131515
F2117117Certificate of AnalysisJan 20, 2025 D131515
A2507496Certificate of AnalysisDec 26, 2024 D131515
A2507497Certificate of AnalysisDec 26, 2024 D131515
A2507500Certificate of AnalysisDec 26, 2024 D131515
F2517235Certificate of AnalysisDec 26, 2024 D131515
K2324179Certificate of AnalysisNov 13, 2023 D131515
H2421123Certificate of AnalysisNov 13, 2023 D131515
G2415342Certificate of AnalysisNov 13, 2023 D131515
F2118062Certificate of AnalysisApr 11, 2023 D131515
F1515085Certificate of AnalysisJan 17, 2023 D131515
D2219052Certificate of AnalysisFeb 24, 2022 D131515
J2323067Certificate of AnalysisFeb 24, 2022 D131515
D2219047Certificate of AnalysisFeb 24, 2022 D131515
D2219044Certificate of AnalysisFeb 24, 2022 D131515
D2219043Certificate of AnalysisFeb 24, 2022 D131515
D2219034Certificate of AnalysisFeb 24, 2022 D131515
A2310398Certificate of AnalysisFeb 24, 2022 D131515

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Chemical and Physical Properties
SolubilitySoluble in DMF,methanol
SensitivityLight sensitive.
Melt Point(°C)245 °C(dec.)
Molecular Weight546.500 g/mol
XLogP3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass546.066 Da
Monoisotopic Mass546.066 Da
Topological Polar Surface Area60.700 Ų
Heavy Atom Count30
Formal Charge0
Complexity564.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds3
Covalently-Bonded Unit Count2
Documents & Articles
Citations of This Product
References
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42. Daxing Cao, Guihua Liu, Ying Wang, Xiaoxue Xia.  (2025)  Repurposing astemizole to kill multidrug-resistant bacteria isolated in general surgery.  MICROBIAL PATHOGENESIS,      [PMID:39929397] [10.1016/j.micpath.2025.107369]
43. Jun Wang, Yongzheng Liu, Chongxiang Sun, Long Chen, Sikai Chen, Xingyu Huang, Zhijia Lu, Chunliu Dong, Yadan Zheng, Zhiyun Zhang, Yanyan Liu, Qianwei Qu, Yanhua Li.  (2025)  Effect of emodin on Streptococcus suis by targeting β-ketoacyl-acyl carrier protein synthase Ⅱ.  PHYTOMEDICINE,      [PMID:40339548] [10.1016/j.phymed.2025.156821]
44. Ziao Zhou, Peng Zhang, Dinghao Chen, Nan Kong, Huayang Liu, Juan Liang, Kai Huang, Huaimin Wang.  (2025)  Cecropin A-Derived Peptide for the Treatment of Osteomyelitis by Inhibiting the Growth of Multidrug-Resistant Bacteria and Eliminating Inflammation.  ACS Nano,      [PMID:40231707] [10.1021/acsnano.4c18858]
45. Yongqing Liu, Tingting Yan, Hongtao Kong, Leizi Chi, Dejun Liu, Shangshang Qin, Yang Wang, Muchen Zhang, En Zhang.  (2025)  Antimicrobial peptide mimic 329 potentiates minocycline against carbapenem-resistant Klebsiella pneumoniae.  BIOORGANIC CHEMISTRY,      [PMID:40311240] [10.1016/j.bioorg.2025.108517]
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