3,4,4'-Trichlorocarbanilide - 10mM in DMSO , CAS No.101-20-2

CAS: 101-20-2 Cat. No.: T420312 Molecular Weight: 315.58 EC Number: 202-924-1 PubChem CID: 7547
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GRADE & PURITY 10mM in DMSO
Synonyms
TCC | DB11155 | CCRIS 4880 | KS-5290 | MegaFresh Antibacterial Deodorant | Personal Care Antibacterial | Triclocarben | Trichlorocarbanilide | TRICLOCARBAN [INN] | Urea-based compound, 11 | CP 78416 | WLN: GR DMVMR CG DG | Dial Odor ArmorOdor Armor | s644
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Status
Price
Qty
1ml
T420312-1ml
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 32 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

3,4,4′-Trichlorocarbanilide(TCC) is employed as bacteriostat and antimicrobial agent in bar soaps3, cosmetics and other persona care prducts1.TCC is a toxic, persistent and potentially bioaccumulative polychlorinated binuclear aromatic urea pesticide.
3,4,4′-Trichlorocarbanilide was used to develop a sensitive analytical method to determine triclocarban and environmental phenols in breast milk using isotope dilution on-line solid-phase extraction coupled with HPLC–tandem mass spectrometry. 3,4,4′-Trichlorocarbanilide was used in quantitative structure-activity relationship (QSAR)analyses conducted to study the co-occurrence of Triclocarban and Triclosan in U.S. Water Resources.

Specifications

Synonyms
TCC | DB11155 | CCRIS 4880 | KS-5290 | MegaFresh Antibacterial Deodorant | Personal Care Antibacterial | Triclocarben | Trichlorocarbanilide | TRICLOCARBAN [INN] | Urea-based compound, 11 | CP 78416 | WLN: GR DMVMR CG DG | Dial Odor ArmorOdor Armor | s644
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Pubchem Sid528769094
Canonical SmilesC1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)Cl)Cl
IUPAC Name1-(4-chlorophenyl)-3-(3,4-dichlorophenyl)urea
InChIKeyICUTUKXCWQYESQ-UHFFFAOYSA-N
INCHI1S/C13H9Cl3N2O/c14-8-1-3-9(4-2-8)17-13(19)18-10-5-6-11(15)12(16)7-10/h1-7H,(H2,17,18,19)
Isomeric SMILES C1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)Cl)Cl
WGK Germany 2
RTECS FE1250000
PubChem CID 7547
Molecular Weight 315.58
Reaxy-Rn 2814890

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassHalobenzenes
Intermediate Tree Nodes Chlorobenzenes
Direct ParentDichlorobenzenes
Alternative Parents Aryl chlorides  Isoureas  Propargyl-type 1,3-dipolar organic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents 1,2-dichlorobenzene - Aryl chloride - Aryl halide - Isourea - Carboximidic acid derivative - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Organooxygen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as dichlorobenzenes. These are compounds containing a benzene with exactly two chlorine atoms attached to it.
External Descriptors ureas - dichlorobenzene - monochlorobenzenes
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
EPHX2 Tchem Bifunctional epoxide hydrolase 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EPHX1 Tchem Epoxide hydrolase 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NLRP3 Tchem NACHT, LRR and PYD domains-containing protein 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EPHX1 Tchem Epoxide hydrolase 1 (644 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AHR Tclin Aryl hydrocarbon receptor (1071 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EPHX2 Tchem Epoxide hydratase (3844 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Raji (5516 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BJ (6930 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B7 Tchem UDP-glucuronosyltransferase 2B7 (787 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B17 Tbio UDP-glucuronosyltransferase 2B17 (197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTT Tchem Huntingtin (19182 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B4 Tbio UDP-glucuronosyltransferase 2B4 (139 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Faah Anandamide amidohydrolase (3907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INS1 (2867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Epoxide hydrolase (46 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver microsome (341 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)254-256°C
Molecular Weight315.600 g/mol
XLogP35.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass313.978 Da
Monoisotopic Mass313.978 Da
Topological Polar Surface Area41.100 Ų
Heavy Atom Count19
Formal Charge0
Complexity308.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Lianxu Wang, Zhen Lei, Sining Yun, Xiaohuan Yang, Rong Chen.  (2023)  Quantitative structure-biotransformation relationships of organic micropollutants in aerobic and anaerobic wastewater treatments.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:38072270] [10.1016/j.scitotenv.2023.169170]
2. Xiao Sihua, Wan Jinquan, Wang Yan, Yan Zhicheng, Ma Yongwen, Sun Jian, Tang Min, Cao Jianye, Chen Jinxin.  (2023)  Distribution, Sources, and Risk Assessment of Emerging Contaminants in the Effluents from Large-Scale Wastewater Treatment Plants in Guangzhou Central Districts, South China.  WATER AIR AND SOIL POLLUTION,  234  (7): (1-17).  [PMID:] [10.1007/s11270-023-06410-9]
3. Tongchen Zhang, Huan Wu, Matin Naghizadeh, Qian Zheng, Sheying Dong.  (2023)  Magnetic Porous Polymer with −OH Groups as Sorbent for Excellent Extraction and Removal of Personal Care Products from Water.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.3c00453]
4. Miao Lei, Chen Siyuan, Yang Hua, Hong Yaqi, Sun Liwen, Yang Jie, Sun Guanjun, Liu Yi, Li Chunyan, Zang Hailian, Cheng Yi.  (2023)  Enhanced bioremediation of triclocarban-contaminated soil by Rhodococcus rhodochrous BX2 and Pseudomonas sp. LY-1 immobilized on biochar and microbial community response.  Frontiers in Microbiology,      [PMID:37065135] [10.3389/fmicb.2023.1168902]
5. Hao Wang, Hanlin Cui, Xiaodan Ma, Carolyn R. Cornell, Liying Zhang, Yijun Ren, Minghan Li, Ying Liu, Shu-Hong Gao, Zhiling Li, Ai-Jie Wang, Jizhong Zhou, Bin Liang.  (2023)  Molecular mechanism of adsorbing triclocarban by the activated sludge in wastewater treatment systems.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.142431]
6. Zhuang Ke, Shen Wang, Wenqi Zhu, Fu Zhang, Wenjing Qiao, Jiandong Jiang, Kai Chen.  (2022)  Genetic bioaugmentation with triclocarban-catabolic plasmid effectively removes triclocarban from wastewater.  ENVIRONMENTAL RESEARCH,      [PMID:35863452] [10.1016/j.envres.2022.113921]
7. Li Chen, Tahir Maqbool, Wanyi Fu, Yulong Yang, Congyu Hou, Jianning Guo, Xihui Zhang.  (2022)  Highly efficient manganese (III) oxide submerged catalytic ceramic membrane for nonradical degradation of emerging organic compounds.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2022.121272]
8. Chunyan Li, Yueling Sun, Guanjun Sun, Hailian Zang, Shanshan Sun, Xinyue Zhao, Ning Hou, Dapeng Li.  (2022)  An amidase and a novel phenol hydroxylase catalyze the degradation of the antibacterial agent triclocarban by Rhodococcus rhodochrous.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:35183828] [10.1016/j.jhazmat.2022.128444]
9. Hao Li, Yikelamu Jilili, Weijun Zhen, Ling Zhao.  (2022)  Preparation, performance and structure-properties relationship of poly (lactic acid)/modified saponite nanocomposites based on thiol-ene click chemistry.  Polymer-Plastics Technology and Materials,      [PMID:] [10.1080/25740881.2021.1948059]
10. Fang Ge, Qun Zhang, Xiaowu Wang.  (2021)  Synthetic and mechanistic aspects of anionic polymerization of methyl methacrylate using tetrabutyl ammonium thioimidate.  JOURNAL OF POLYMER SCIENCE,  59  (9): (764-774).  [PMID:] [10.1002/pol.20200824]
11. Wan-Jun Long, Hai-Long Wu, Tong Wang, Ming-Yue Dong, Ru-Qin Yu.  (2020)  Interference-free analysis of multi-class preservatives in cosmetic products using alternating trilinear decomposition modeling of liquid chromatography diode array detection data.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2020.105847]
12. Qiao Zhong, Ying Deng, Huaming Qin, Huase Ou, Yanfen Qu, Jinshao Ye.  (2020)  Metabolic network and recovery mechanism of Escherichia coli associated with triclocarban stress.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:32858325] [10.1016/j.ecoenv.2020.111140]
13. Jiping Ma, Shuang Li, Gege Wu, Maryam Arabi, Feng Tan, Yafeng Guan, Jinhua Li, Lingxin Chen.  (2020)  Preparation of magnetic metal-organic frameworks with high binding capacity for removal of two fungicides from aqueous environments.  JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,      [PMID:] [10.1016/j.jiec.2020.07.010]
14. Yanxia Li, Hongna Zhang, Yiting Chen, Lu Huang, Zian Lin, Zongwei Cai.  (2019)  Core–Shell Structured Magnetic Covalent Organic Framework Nanocomposites for Triclosan and Triclocarban Adsorption.  ACS Applied Materials & Interfaces,      [PMID:31180623] [10.1021/acsami.9b06953]
15. Chang Liu, Donghui Liu, Xueke Liu, Xu Jing, Fulin Zong, Peng Wang, Zhiqiang Zhou.  (2017)  Deep eutectic solvent-based liquid phase microextraction for the determination of pharmaceuticals and personal care products in fish oil.  NEW JOURNAL OF CHEMISTRY,  41  (24): (15105-15109).  [PMID:] [10.1039/C7NJ03350H]
16. Lulu Chen, Xinyuan Zhang, Ruonan Feng, Xiaona Dong, Junhe Lu, Canlan Jiang.  (2024)  Critical roles of soil composition and pollutant properties on the degradation of PPCPs during ferrous/persulfate processes.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.153390]
17. Ping He, Qian Zheng, Matin Naghizadeh, Guiqi Huang, Sheying Dong.  (2024)  Efficient and recycled magnetic self-stirring hollow fiber-solid/liquid phase system: An extraction and removal technique for personal care pollutants.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2024.124002]
18. Jingwei Wang, Pan Zhao, Jiaxin Wang, Shuzhen Li, Qiao Ma.  (2025)  Responses of microbial communities in coastal sediments exposed to triclocarban and triclosan.  MARINE POLLUTION BULLETIN,      [PMID:39798524] [10.1016/j.marpolbul.2025.117530]
19. ZiXuan Wang, Hao Zheng, Zhengchun Cai, Haian Xia.  (2024)  Ring-opening copolymerization of ε-caprolactone and δ-valerolactone to cyclic polyesters by a bimolecular system.  JOURNAL OF APPLIED POLYMER SCIENCE,  142  (2): (e56337).  [PMID:] [10.1002/app.56337]
20. Yitong Yan, Jin Qian, Yin Liu, Jing Hu, Bianhe Lu, Shasha Zhao, Shuai Jin, Yuxuan He, Kailin Xu.  (2024)  Short-term exposure to triclocarban alters microbial community composition and metabolite profiles in freshwater biofilms.  CHEMOSPHERE,      [PMID:38908443] [10.1016/j.chemosphere.2024.142674]
21. Mingyu Sang, Shuyu Liu, Haohao Yan, Bing Zhang, Siyuan Chen, Bowen Wu, Tian Ma, Hanyi Jiang, Peichao Zhao, Guanjun Sun, Xinyan Gao, Hailian Zang, Yi Cheng, Chunyan Li.  (2024)  Synergistic detoxification efficiency and mechanism of triclocarban degradation by a bacterial consortium in the liver-gut-microbiota axis of zebrafish (Danio rerio).  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:38608581] [10.1016/j.jhazmat.2024.134178]
22. Ting-Ting He, Xin Li, Jie-Zhi Ma, Yuan Yang, Shiye Zhu, Jianhua Zeng, Lin Luo, Yu-Long Yin, Lin-Ying Cao.  (2024)  Triclocarban and triclosan promote breast cancer progression in vitro and in vivo via activating G protein-coupled estrogen receptor signaling pathways.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:38679099] [10.1016/j.scitotenv.2024.172782]
23. Jun-Jie Gu, Xiao-Xiao Dou, Jin-Long Zhou, Si-Yuan Guo, Ashiwin Vadiveloo, Xiao-Ling Zhang, Kai-Yuan Li, Dong-Zhi Chen, Feng Gao.  (2025)  Phytohormone-augmented microalgae: A dual-functional solution for pharmaceutical contaminants removal and resource recovery.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40749654] [10.1016/j.jhazmat.2025.139379]
24. Jia-Hui Yang, Wei-Lin Guo, Zhe-Qi Lian, Qi Su, Xin-Yi Zhao, Wen-Li Guo, Nian-Si Fan, Ren-Cun Jin.  (2025)  Regulation mechanism and resistant strain based bioaugmentation of anammox consortia in response to triclocarban.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.167745]
25. Xinyu Fang, Jinfeng Zhao, Simin Wu, Peng Liao, Guiping Guan.  (2025)  Investigating the mechanisms of Triclocarban-induced liver injury: A comprehensive analysisbased on network toxicology and in vivo experiments.  ENVIRONMENTAL POLLUTION,      [PMID:40774534] [10.1016/j.envpol.2025.126953]
26. Jiao Guan, Xin Yan, Yajing Zhao, Yinhe Sun, Xin Peng.  (2018)  Binding studies of triclocarban with bovine serum albumin: Insights from multi-spectroscopy and molecular modeling methods.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:29777928] [10.1016/j.saa.2018.04.070]
27. Qi Lou, Rongguang Shi, Rui Guan, Jing Lan, Yaoyao Wang, Yaru Li, Wansong Zong, Zongshan Zhao.  (2025)  Enhanced binding of triclocarban to catalase induced by coexisting nanoplastics.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:40449463] [10.1016/j.saa.2025.126476]
28. Zijie Sun, Yaoyao Wang, Rui Guan, Hongbin Liu, Jing Lan, Hui Xue, Wansong Zong.  (2025)  The decreased enzyme activity of trypsin resulted from its conformation changes in presence of triclocarban.  JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING,      [PMID:40524413] [10.1080/10934529.2025.2518848]
29. Jianmin Sang, Kangjian Sang, Xuewei Ding, Zhengzheng Wang, Lieying Fan.  (2025)  Elucidating the novel mechanism of organochlorine fungicides in inhibiting human and rat gonadal 3β-hydroxysteroid dehydrogenase via molecular docking and 3D-QSAR analysis.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,      [PMID:41177112] [10.1016/j.ecoenv.2025.119331]
30. Ruinan Zhao, Pengyuan Liu, Yaoyang Wu, Hongyan Bi, Jiaoying He, Jie Zhang, Yanfu Qu, Xiaohong Chen, Zhuo Chen.  (2025)  Triclocarban exposure at environmentally relevant concentrations perturbs the gut microbiota and metabolic profile in Rana taihangensis (Anura, Ranidae) tadpoles.  Frontiers in Microbiology,      [PMID:41472804] [10.3389/fmicb.2025.1740880]
31. Chongshu Li, Changlei Wang, Qiying Lu, Jie Zhang, Yan Long, Jinshao Ye.  (2026)  Insightful approach for screening triclocarban-degrading microbes via enzyme-guided strategy: Detoxification regulation and energy metabolism by Diaphorobacter polyhydroxybutyrativorans.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:] [10.1016/j.jhazmat.2026.141660]
32. Jiayin Zhao, Yu Qiao, Liju Tan, Huiru Li, Jiangtao Wang.  (2026)  A smartphone-based quantum dot molecularly imprinted ratiometric fluorescent sensor for rapid determination of triclosan.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2026.117803]
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