3,4-Dichloroaniline - 10mM in DMSO , CAS No.95-76-1

CAS: 95-76-1 Cat. No.: D661315 Molecular Weight: 162.02 Beilstein Registry Number: 636837 EC Number: 202-448-4
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GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Status
Price
Qty
1ml
D661315-1ml
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

product description:

3,4-Dichloroaniline (3,4-DCA) is an aromatic amine and is a model environmental contaminant. It is an important precursor for the synthesis and degradation product of several herbicides. It is a metabolite of commonly applied herbicide, 3,4-dichloropropionanilide or propanil. Biodegradation kinetics of 3,4-DCA has been reported. Mechanism of degradation of aqueous 3,4-DCA in a novel dielectric barrier discharge plasma reactor has been studied. 1,2-dichlorobenzene, 2-chloro-1,4-benzoquinone, 3,4-dichlorophenyl isocyanate, 2-chlorohydroquinone, 3,4-dichloronitrobenzene and 3,4-dichlorophenol were identified as degradation intermediates by GC-MS analysis.


application:

3,4-Dichloroaniline may be employed as derivatization reagent for the HPLC analysis of perfluorooctanoic acid (PFOA).

Specifications

Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES C1=CC(=C(C=C1N)Cl)Cl
WGK Germany 3
RTECS BX2625000
UN Number 3442
Packing Group II
Molecular Weight 162.02
Beilstein 636837
Reaxy-Rn 636837
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=636837&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Flash Point(°F)275 °F
Flash Point(°C)135 °C
Boil Point(°C)272°C
Melt Point(°C)69-71°C
Citations of This Product
References
1. Qidong Yu, Wenmin Zhang, Hui Chen, Jingyi Wang, Zhiyong Wang, Qingqing Ding, Lan Zhang.  (2023)  Synthesis of stable and efficient amide-based covalent organic frameworks fiber coatings for the improved solid-phase microextraction of polar aromatic amines.  ANALYTICA CHIMICA ACTA,      [PMID:37996159] [10.1016/j.aca.2023.342002]
2. Yibo Dong, Xiaolong Yao, Wanping Zhang, Xiaomao Wu.  (2023)  Development of Simultaneous Determination Method of Pesticide High Toxic Metabolite 3,4-Dichloroaniline and 3,5 Dichloroaniline in Chives Using HPLC-MS/MS.  Foods,  12  (15): (2875).  [PMID:37569143] [10.3390/foods12152875]
3. Miao Lei, Chen Siyuan, Yang Hua, Hong Yaqi, Sun Liwen, Yang Jie, Sun Guanjun, Liu Yi, Li Chunyan, Zang Hailian, Cheng Yi.  (2023)  Enhanced bioremediation of triclocarban-contaminated soil by Rhodococcus rhodochrous BX2 and Pseudomonas sp. LY-1 immobilized on biochar and microbial community response.  Frontiers in Microbiology,      [PMID:37065135] [10.3389/fmicb.2023.1168902]
4. Hao Wang, Hui Yun, Minghan Li, Hanlin Cui, Xiaodan Ma, Yanqing Zhang, Xuanyuan Pei, Liying Zhang, Ke Shi, Zhiling Li, Bin Liang, Aijie Wang, Jizhong Zhou.  (2022)  Fate, toxicity and effect of triclocarban on the microbial community in wastewater treatment systems.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:36007371] [10.1016/j.jhazmat.2022.129796]
5. Zhuang Ke, Shen Wang, Wenqi Zhu, Fu Zhang, Wenjing Qiao, Jiandong Jiang, Kai Chen.  (2022)  Genetic bioaugmentation with triclocarban-catabolic plasmid effectively removes triclocarban from wastewater.  ENVIRONMENTAL RESEARCH,      [PMID:35863452] [10.1016/j.envres.2022.113921]
6. Chunyan Li, Yueling Sun, Guanjun Sun, Hailian Zang, Shanshan Sun, Xinyue Zhao, Ning Hou, Dapeng Li.  (2022)  An amidase and a novel phenol hydroxylase catalyze the degradation of the antibacterial agent triclocarban by Rhodococcus rhodochrous.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:35183828] [10.1016/j.jhazmat.2022.128444]
7. Hao Wang, Hui Yun, Xiaodan Ma, Minghan Li, Mengyuan Qi, Ling Wang, Zhiling Li, Shuhong Gao, Yu Tao, Bin Liang, Aijie Wang.  (2022)  Bioelectrochemical catabolism of triclocarban through the cascade acclimation of triclocarban-hydrolyzing and chloroanilines-oxidizing microbial communities.  ENVIRONMENTAL RESEARCH,      [PMID:35123970] [10.1016/j.envres.2022.112880]
8. Qingqing Li, Wenmin Zhang, Yuheng Guo, Hui Chen, Qingqing Ding, Lan Zhang.  (2021)  Oxygenated carbon nanotubes cages coated solid-phase microextraction fiber for selective extraction of migrated aromatic amines from food contact materials.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:33857834] [10.1016/j.chroma.2021.462031]
9. Bing Shen, Hong-Cui Liu, Wen-Bin Ou, Grant Eilers, Sheng-Mei Zhou, Fan-Guo Meng, Chun-Qi Li, Yong-Quan Li.  (2015)  Toxicity induced by Basic Violet 14, Direct Red 28 and Acid Red 26 in zebrafish larvae.  JOURNAL OF APPLIED TOXICOLOGY,  35  (12): (1473-1480).  [PMID:25727789] [10.1002/jat.3134]
10. Xiaowen Du, Pan Zhan, Ning Gan, Yuting Cao, Tianhua Li, Weiguo Sang, Lihong Wang.  (2013)  Highly Selective Molecular Recognition and Ultrasensitive Detection of 3,4-dichloroaniline Based on Molecularly Imprinted Sol-Gel Film Combined with Multi-Walled Carbon Nanotubes.  JOURNAL OF THE ELECTROCHEMICAL SOCIETY,  160  (10): (H742).  [PMID:] [10.1149/2.082310jes]
11. Zhou-Yang Li, Min Li, Xue-Ning Zhang, Kun Zheng, Han-Bing Xiao, Ai-Jie Wang, Yi-Lu Sun.  (2025)  Mechanisms linking triclocarban biotransformation to functional response in sulfur-metabolism biofilm.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40690841] [10.1016/j.jhazmat.2025.139255]
12. Xu-Hui Li, Yan-Hong Li, Yuan-Yuan Cui, Cheng-Xiong Yang.  (2025)  Ionic liquid functionalized magnetic microporous organic network for efficient extraction of phenoxyacetic acid herbicides from vegetables.  FOOD CHEMISTRY,      [PMID:40729996] [10.1016/j.foodchem.2025.145699]
13. Zhuang Wang, Le Yu.  (2023)  An Insight into the Combined Toxicity of 3,4-Dichloroaniline with Two-Dimensional Nanomaterials: From Classical Mixture Theory to Structure-Activity Relationship.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (4): (3723).  [PMID:36835146] [10.3390/ijms24043723]
14. Yinxuan Lin, Jiao Yu, Meng Wang, Lingling Wu.  (2022)  Toxicity of single and combined 4-epianhydrotetracycline and cadmium at environmentally relevant concentrations on the zebrafish embryos (Danio rerio).  ENVIRONMENTAL POLLUTION,      [PMID:36341832] [10.1016/j.envpol.2022.120543]
15. Shouchun Xiao, Shengchen Lv, Zheng Cheng, Caiwei Hu, Pengxi Li, Fang Nan, Xueke Liu, Donghui Liu, Zhiqiang Zhou, Peng Wang.  (2021)  A Simple Method for the Determination of Pharmaceutical and Personal Care Products in Fish Tissue Based on Matrix Solid-Phase Dispersion.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:34930006] [10.1021/acs.jafc.1c05232]
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