3-(Diethylamino)propylamine - ≥97% , CAS No.104-78-9

CAS: 104-78-9 Cat. No.: D615689 Molecular Weight: 130.23 Beilstein Registry Number: 741879 EC Number: 203-236-4
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
104-78-9|3-Diethylaminopropylamine|3-(Diethylamino)propylamine|N,N-Diethyl-1,3-propanediamine|1,3-PROPANEDIAMINE, N,N-DIETHYL-|(3-Aminopropyl)Diethylamine|3-Aminopropyldiethylamine|Diethylaminopropylamine|Diethylaminotrimethylenamine|N1,N1-Diethylpropane-
Storage
Room temperature
Shipped In
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Size
Status
Price
Qty
50g
D615689-50g
3

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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

3-(Diethylamino)propylamine (3-(diethylamino)-1-propylamine, DEAPA) is a diamine.
3-(Diethylamino)propylamine may be used in the preparation of: Biocompatible polyampholyte-coated (poly(acrylic acid)-co-3-(diethylamino)-propylamine magnetite nanoparticles (PAMNPs). Hyaluronic acid grafted with 3-diethylaminopropyl (DEAP) group (HA-g-DEAP) nanoparticles for use as a drug delivery vehicle. DEAPA-modified poly(vinyl alcohol) (PVA) polymers that can be employed in gene silencing. It may also be used to introduce cationic groups during the surface modification of microfibrillated cellulose (MFC).

Specifications

Synonyms
104-78-9 | 3-Diethylaminopropylamine | 3-(Diethylamino)propylamine | N, N-Diethyl-1, 3-propanediamine | 1, 3-PROPANEDIAMINE, N, N-DIETHYL- | (3-Aminopropyl)Diethylamine | 3-Aminopropyldiethylamine | Diethylaminopropylamine | Diethylaminotrimethylenamine | N1, N1-Diethylpropane-
Specifications & Purity
≥97%
Storage
Room temperature
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥97%
Names and Identifiers
Canonical SmilesCCN(CC)CCCN
IUPAC NameN',N'-diethylpropane-1,3-diamine
InChIKeyQOHMWDJIBGVPIF-UHFFFAOYSA-N
INCHI1S/C7H18N2/c1-3-9(4-2)7-5-6-8/h3-8H2,1-2H3
Isomeric SMILES CCN(CC)CCCN
WGK Germany 1
RTECS TX7350000
UN Number 2684
Packing Group III
Molecular Weight 130.23
Beilstein 741879
Reaxy-Rn 741879
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=741879&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClassOrganonitrogen compounds
SubclassAmines
Intermediate Tree Nodes Tertiary amines
Direct ParentTrialkylamines
Alternative Parents Organopnictogen compounds  Monoalkylamines  Hydrocarbon derivatives  
Molecular FrameworkAliphatic acyclic compounds
Substituents Tertiary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Primary aliphatic amine - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as trialkylamines. These are organic compounds containing a trialkylamine group, characterized by exactly three alkyl groups bonded to the amino nitrogen.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
H2318027Certificate of AnalysisAug 22, 2023 D615689
H2318028Certificate of AnalysisAug 22, 2023 D615689
H2318033Certificate of AnalysisAug 22, 2023 D615689
Chemical and Physical Properties
SolubilityFully miscible in water
SensitivityAir sensitiv
Refractive Index1.4416
Flash Point(°F)125.6 °F
Flash Point(°C)53℃
Boil Point(°C)159°C
Melt Point(°C)-60°C
Molecular Weight130.229 g/mol
XLogP30.400
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass130.147 Da
Monoisotopic Mass130.147 Da
Topological Polar Surface Area29.300 Ų
Heavy Atom Count9
Formal Charge0
Complexity50.900
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Yanhua Zhang, Hui Huang, Hao Fu, Meng Zhao, Zhihua Wu, Yang Dong, He Li, Yourong Duan, Ying Sun.  (2019)  Dual-mode US/MRI nanoparticles delivering siRNA and Pt(IV) for ovarian cancer treatment.  RSC Advances,  (57): (33302-33309).  [PMID:35529112] [10.1039/C9RA03681D]
2. Dongfang Liu, Youlin Ma, Jiang Tan, Lu Wang, Quanwu Tang, Hongsheng Lu.  (2018)  CO2 regulates phase transition of sodium oleate and 3-(diethylamino)-propylamine in aqueous solution.  JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY,      [PMID:] [10.1080/01932691.2018.1461642]
3. Rui Zhang, Xiao Luo, Qi Yang, Fan Cao, Shupanxiang Chen, Zhiwu Liang.  (2016)  Impact of the Inter- and Intramolecular Tertiary Amino Group on the Primary Amino Group in the CO2 Absorption Process.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.6b01404]
4. Zunbin Duan, Rui Li, He Bian, Yanfang Wang, Xue Zhang, Ziqiang Cheng, Danni Liu, Yang Li, Shuai Zhang, Guangbo Qu, Paul K. Chu, Jiahong Wang.  (2025)  Large-Scale synthesis of crystalline phosphorus nanosheets with superior air-water stability and flame-retardancy ability.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.159566]
5. Wang Tang, Tianxiong Liu, Hongxia Gao, Shaofei Wang, Min Zhou, Ningbo Yu, Zhiwu Liang.  (2025)  Study on artificial neural networks and structure–activity relationship for constructing viscosity correlations of amine aqueous solutions based on chemical structure information.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.131912]
6. Xi Tang, Ge Gao, Wufeng Jiang, Bin Xu, Fan Wu, Cong Luo, Xiaoshan Li, Liqi Zhang.  (2025)  The structure–activity relationship for CO2 absorption heat of chain diamines: Effects of amino types, methyl/ethyl groups, and chain lengths.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.160838]
7. Jiyuan Zhang, Guojun Ji, Rui Cao, Bo Zhang, Qiang Li, Jianbin Zhang.  (2025)  Density, Viscosity, and Volumetric Properties of (2-Propoxyethanol + 3-Diethylamino Propylamine) Mixed Solutions at T = 298.15–318.15 K and Atmospheric Pressure for Absorption of CO2.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/acs.jced.4c00712]
8. Na An, Peng-Cheng Mei, Ao Li, Xiu-Feng Fu, Xin-Ze Wu, Han-Peng Jiang, Quan-Fei Zhu, Yu-Qi Feng.  (2025)  Derivatization-Assisted Acoustic Ejection Mass Spectrometry for High-Throughput FAHFA Prescreening.  ANALYTICAL CHEMISTRY,      [PMID:40305168] [10.1021/acs.analchem.5c01004]
9. Ziyong Li, Qingdan Huang, Tingyan Wang, Huihong Huang, Haoyong Song.  (2025)  Influences of Diamine Molecular Structures on the Phase-Change CO2 Capture From Flue Gas.  Greenhouse Gases-Science and Technology,      [PMID:] [10.1002/ghg.2347]
10. Zhaoran Wang, Jiawei Liu, Jiayao Wen, Wei He, Luqing Zhang, Yabin Zhang, Lei Ye.  (2025)  Tri-modal adhesion switchable hydrogel with precise regulation of interfacial states via a solvent microenvironment reconstruction strategy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.164952]
11. Huajie Qiu, Qinghai Long, Yutao Bai, Xuanang Fu, Chao Liu, Guohua Jing, Zuoming Zhou, Bihong Lv.  (2025)  An ionic liquid phase change absorbent capable of low-temperature regeneration: Investigation of phase change and regeneration mechanism.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.165388]
12. Guangjie Chen, Guangying Chen, Li Sze Lai, Zhiwei Zhang, Xiaodi Chen, Yun Hin Taufiq-Yap.  (2025)  Investigation of the Performance and Mechanism of CO2 Capture Using Novel MEA/Polyamine/Sulfolane Biphasic Absorbents.  Separations,  12  (12): (342).  [PMID:] [10.3390/separations12120342]
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