4-Fluoro-3-nitrobenzoic Acid - 10mM in DMSO , CAS No.453-71-4

CAS: 453-71-4 Cat. No.: F660992 Molecular Weight: 185.11 Beilstein Registry Number: 9(1)165 EC Number: 207-221-3

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

application：

4-Fluoro-3-nitrobenzoic acid was used:

as starting reagent in the preparation of novel benzimidazoles having antimycobacterial activity in preparation of series of novel acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors containing benzimidazole core structure

in preparation of bis(heterocyclic) skeletal precursors for the Pictet-Spengler reaction

in solid-phase synthesis of trisubstituted [1,3,5]triazino[1,2-a]benzimidazole-2,4(3H,10H)-diones

Specifications

Specifications & Purity

10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: C1=CC(=C(C=C1C(=O)O)[N+](=O)[O-])F
• WGK Germany: 2
• Molecular Weight: 185.11
• Beilstein: 9(1)165
• Reaxy-Rn: 2107562
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2107562&ln=

Chemical and Physical Properties

• Boil Point(°C): 92°/15mm
• Melt Point(°C): 123-126°C

References

1. Liu Hongmei, Chang Hong, Lv Jia, Jiang Cong, Li Zhenxi, Wang Fei, Wang Hui, Wang Mingming, Liu Chongyi, Wang Xinyu, Shao Naimin, He Bingwei, Shen Wanwan, Zhang Qiang, Cheng Yiyun.  (2016)  Screening of efficient siRNA carriers in a library of surface-engineered dendrimers.  Scientific Reports,  6  (1): (1-11).  [PMID:27121799] [10.1038/srep25069]