Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 26 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .
| Isomeric SMILES | CC(C)(C)CC(C)(C)C1=CC=C(C=C1)O |
|---|---|
| UN Number | 3077 |
| Packing Group | III |
| Molecular Weight | 206.32 |
| Reaxy-Rn | 513992 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=513992&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Flash Point(°F) | 296.6 °F |
|---|---|
| Flash Point(°C) | 147 °C |
| Boil Point(°C) | 175 °C/30 mmHg(lit.) |
| Melt Point(°C) | 79-82°C(lit.) |
| 1. Cuicui Wang, Jierong Zheng, Sufang Wang, Aijuan Zhou, Xin Kong, Bowei Zhao, Houfen Li, Xiuping Yue. (2023) Efficient elimination of nonylphenol and 4-tert-octylphenol by weak electrical stimulated anaerobic microbial processes. CHEMOSPHERE, [PMID:36758818] [10.1016/j.chemosphere.2023.138085] |
| 2. Yan Wu, Panpan Cao, Yanhao Jiang, Yanjuan Liu, Yuefei Zhang, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Ingenious introduction of aminopropylimidazole to tune the hydrophobic selectivity of dodecyl-bonded stationary phase for environmental organic pollutants. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2022.107933] |
| 3. Chen Jinyang, Huang Xiaozhou, Ye Ruihong, Huang Dihui, Wang Yanjun, Chen Sheng. (2022) Fabrication of a novel electrochemical sensor using conductive MOF Cu-CAT anchored on reduced graphene oxide for BPA detection. JOURNAL OF APPLIED ELECTROCHEMISTRY, 52 (11): (1617-1628). [PMID:] [10.1007/s10800-022-01735-5] |
| 4. Kaixing Luo, Yu Luo, Yanjuan Liu, Yuefei Zhang, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Hydrophobic and hydrophilic selectivity of a multifunctional carbonyldiimidazolium/dodecyl modified silica stationary phase. JOURNAL OF CHROMATOGRAPHY A, [PMID:35810643] [10.1016/j.chroma.2022.463300] |
| 5. Leikeqing Shen, Jiayang Zhang, Xueping Dang, Huaixia Chen, Hongmei Yuan. (2022) Preparation and application of a nanocomposite of dopamine modified zirconium metal organic framework and polythiophene for solid-phase microextraction/gas chromatography of phenols released from polycarbonate materials. JOURNAL OF CHROMATOGRAPHY A, [PMID:35752153] [10.1016/j.chroma.2022.463187] |
| 6. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations. JOURNAL OF CHROMATOGRAPHY A, [PMID:35085896] [10.1016/j.chroma.2022.462834] |
| 7. Jinyang Chen, Jiamei Wang, Ruihong Ye, Dihui Huang, Sheng Chen. (2021) An electrochemical sensor based on a glassy carbon electrode modified with sandwich structured ZIF-67@rGO for bisphenol A measurement. Analytical Methods, 13 (47): (5777-5786). [PMID:34825246] [10.1039/D1AY01542G] |
| 8. Jiayang Zhang, Xueping Dang, Jiahuan Dai, Yuling Hu, Huaixia Chen. (2021) Simultaneous detection of eight phenols in food contact materials after electrochemical assistance solid-phase microextraction based on amino functionalized carbon nanotube/polypyrrole composite. ANALYTICA CHIMICA ACTA, [PMID:34627510] [10.1016/j.aca.2021.338981] |
| 9. Xu JING, Hao-Yue XUE, Xin HUANG, Hui-Yuan LI, Xiao-Wen WANG, Li-Yan JIA. (2021) An Effervescence-assisted Centrifuge-less Dispersive Liquid-Phase Microextraction Based on Solidification of Switchable Hydrophilicity Solvents for Detection of Alkylphenols in Drinks. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, [PMID:] [10.1016/S1872-2040(21)60100-7] |
| 10. Wenfei Zhao, Xu Jing, Yaqin Tian, Cuiping Feng. (2020) Magnetic Fe3O4 @ porous activated carbon effervescent tablet-assisted deep eutectic solvent-based dispersive liquid–liquid microextraction of phenolic endocrine disrupting chemicals in environmental water. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2020.105416] |
| 11. Jiao Yang, Qingyi Huang, Huan Liu, Xiong Zhou, Zhuoquan Huang, Quansheng Peng, Chunhong Liu. (2020) 4-Nonylphenol and 4-tert-octylphenol induce anxiety-related behaviors through alternation of 5-HT receptors and transporters in the prefrontal cortex. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, [PMID:31911191] [10.1016/j.cbpc.2020.108701] |
| 12. Dezhi Yang, Yingdong Wang, Jianbo Peng, Chun Xun, Yaling Yang. (2019) A green deep eutectic solvents microextraction coupled with acid-base induction for extraction of trace phenolic compounds in large volume water samples. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:31002967] [10.1016/j.ecoenv.2019.04.021] |
| 13. Xingyun Zhao, Shengju Liu, Jiaxi Peng, Xin Li, Huan Niu, Hongyan Zhang, Li Wang, Ren’an Wu. (2018) Facile one-pot synthesized hydrothermal carbon from cyclodextrin: A stationary phase for hydrophilic interaction liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:30509619] [10.1016/j.chroma.2018.11.064] |
| 14. Dezhi Yang, Guixiang Li, Lan Wu, Yaling Yang. (2018) Ferrofluid-based liquid-phase microextraction: Analysis of four phenolic compounds in milks and fruit juices. FOOD CHEMISTRY, [PMID:29739611] [10.1016/j.foodchem.2018.04.038] |
| 15. Jing Li, Qingxiang Zhou, Yalin Wu, Yongyong Yuan, Yongli Liu. (2017) Investigation of nanoscale zerovalent iron-based magnetic and thermal dual-responsive composite materials for the removal and detection of phenols. CHEMOSPHERE, [PMID:29274993] [10.1016/j.chemosphere.2017.12.093] |
| 16. Liu Ruimei, Feng Feng, Chen Guolin, Liu Zhimin, Xu Zhigang. (2016) Barbell-shaped stir bar sorptive extraction using dummy template molecularly imprinted polymer coatings for analysis of bisphenol A in water. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408 (19): (5329-5335). [PMID:27225173] [10.1007/s00216-016-9628-3] |
| 17. Shuangqiao Ju, Yaling Yang, Mousheng Liu. (2015) Rapid Determination of Phenolics in Food Packaging by Magnetic Solid-Phase Extraction and High-Performance Liquid Chromatography. ANALYTICAL LETTERS, [PMID:] [10.1080/00032719.2015.1004075] |
| 18. Jianjun Shu, Pengfei Xie, Danni Lin, Rongfeng Chen, Jiang Wang, Beibei Zhang, Mingming Liu, Hanlan Liu, Fan Liu. (2013) Two highly stable and selective solid phase microextraction fibers coated with crown ether functionalized ionic liquids by different sol–gel reaction approaches. ANALYTICA CHIMICA ACTA, [PMID:24331051] [10.1016/j.aca.2013.11.006] |
| 19. Mingming Liu, Xin Zhou, Yingyi Chen, Hanlan Liu, Xionghan Feng, Guohong Qiu, Fan Liu, Zhaorui Zeng. (2010) Innovative chemically bonded ionic liquids-based sol–gel coatings as highly porous, stable and selective stationary phases for solid phase microextraction. ANALYTICA CHIMICA ACTA, [PMID:21094387] [10.1016/j.aca.2010.10.004] |
| 20. Jin-Yang Chen, Ying-Xin Weng, Yong-He Han, Rui-Hong Ye, Di-Hui Huang. (2024) A novel pencil graphite electrode modified with an iron-based conductive metal-organic framework exhibited good ability in simultaneous sensing bisphenol A and bisphenol S. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:38330872] [10.1016/j.ecoenv.2024.116065] |
| 21. Yibo Yan, Ruilin Yang, Yanan Wang, Yinan Wu, Xiaofei Gu, Xiaoqiang Qiao. (2024) Esterified styrene-maleic acid copolymer modified silica as mixed-mode polymer-brush stationary phases for chromatographic separation. JOURNAL OF CHROMATOGRAPHY A, [PMID:39116685] [10.1016/j.chroma.2024.465227] |
| 22. Zhuo Wang, Yuefan Liu, Hao Wang, Weiqian Liang, Zhi-Wei Li, Gangfeng Ouyang. (2024) Mild and friendly preparation of a high-surface porous organic polymers and its application for sensitive detections of endocrine disrupting chemicals. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.110905] |
| 23. Zhigang Xu, Zailei Yang, Zhimin Liu. (2014) Development of dual-templates molecularly imprinted stir bar sorptive extraction and its application for the analysis of environmental estrogens in water and plastic samples. JOURNAL OF CHROMATOGRAPHY A, [PMID:25037774] [10.1016/j.chroma.2014.06.093] |
| 24. Zhenjun Zhao, Jingyi Chi, Zhang FangFang, Yinglin Song, Wenda Xv, Yan Li, Hui Shi. (2025) Impact of the environmental endocrine disruptor 4-octylphenol on reproductive function in pubertal male mice. ENVIRONMENTAL RESEARCH, [PMID:40187393] [10.1016/j.envres.2025.121530] |
| 25. Wang Yiyu, Su Huijun, Liu Ning, Yang Naiwang, Gao Pingqiang. (2025) Distribution of synthetic antioxidants in outdoor and educational indoor dusts and assessment of human exposure. ENVIRONMENTAL GEOCHEMISTRY AND HEALTH, 47 (5): (1-14). [PMID:40281297] [10.1007/s10653-025-02496-8] |
| 26. Jiawen Hong, Junhua Zhao, Hexin Wang, Jiesai Ma, Ruo Wang, Shen Wang, Yangjun Mao, Wenfeng Shen, Lianbang Wang. (2025) Sensitive detection of the toxic impurity 4-aminophenol and acetaminophen via an electrochemical sensor based on MOF-808/AgNWs/Nafion/GCE. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.116540] |
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