≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer.
Application：
Umbelliferyl Arachidonate also known as 7-Hydroxycoumarinyl Arachidonate was used as a fluorogenic substrate for developing a fluorescence-based assay to evaluate the inhibitors against human recombinant monoacylglycerol lipase.
| Excitation and Emision Ranges | λex 360 nm,λem 460 nm;λex 335 nm,λem 450 nm |
|---|
| Pubchem Sid | 488200851 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488200851 |
| Canonical Smiles | CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC1=CC2=C(C=C1)C=CC(=O)O2 |
| IUPAC Name | (2-oxochromen-7-yl) (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate |
| InChIKey | SFTGFGOBCQCZDY-DOFZRALJSA-N |
| INCHI | 1S/C29H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(30)32-26-22-20-25-21-23-29(31)33-27(25)24-26/h6-7,9-10,12-13,15-16,20-24H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15- |
| Isomeric SMILES | CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC1=CC2=C(C=C1)C=CC(=O)O2 |
| WGK Germany | 1 |
| PubChem CID | 35025479 |
| Molecular Weight | 448.59 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Coumarins and derivatives |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Coumarins and derivatives |
| Alternative Parents | Phenol esters 1-benzopyrans Pyranones and derivatives Fatty acid esters Heteroaromatic compounds Lactones Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Coumarin - Benzopyran - Phenol ester - 1-benzopyran - Fatty acid ester - Pyranone - Benzenoid - Pyran - Fatty acyl - Heteroaromatic compound - Lactone - Carboxylic acid ester - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Oxacycle - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organic oxide - Carbonyl group - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 A2628045 | Certificate of Analysis | Feb 03, 2026 | H331434 |
| D2311519 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311535 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311536 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311537 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311542 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311549 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311559 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311565 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311837 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| D2311863 | Certificate of Analysis | Jan 16, 2026 | H331434 |
| Solubility | Soluble in DMSO (50 mg/ml), ethanol (35 mg/ml), ethanol:PBS (pH 7.2)(1:1) (~50 μg/ml), DMF, and water (50 μg/ml) at 25° C. |
|---|---|
| Refractive Index | n20D1.54 (Predicted) |
| Boil Point(°C) | 584.66° C at 760 mmHg (Predicted) |
| Molecular Weight | 448.600 g/mol |
| XLogP3 | 8.200 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 16 |
| Exact Mass | 448.261 Da |
| Monoisotopic Mass | 448.261 Da |
| Topological Polar Surface Area | 52.600 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 713.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 4 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 4 |
| Covalently-Bonded Unit Count | 1 |
