7-O-(Amino-PEG4)-paclitaxel - ≥99.8% , CAS No.O767769

CAS: O767769 Cat. No.: O767769 Molecular Weight: 1101.19

GRADE & PURITY ≥99.8%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

7-O - (Amino-PEG4) - paclitaxel is a PEG based drug linker conjugate used for ADC, comprising a paclitaxel moiety and an amino group. Amino groups can react with carboxylic acids, activated NHS esters, carbonyl groups (ketones, aldehydes), etc. 7-O - (Amino-PEG4) - paclitaxel can be used for the synthesis of ADCs.

Powder -20°C 3 years；In solvent -80°C 6 months，-20°C 1 month

In vitro research

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Specifications

Specifications & Purity

≥99.8%

Biochemical and Physiological Mechanisms

7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclit

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99.8%

Names and Identifiers

• Molecular Weight: 1101.19