[Arg14,Lys15]Nociceptin, CAS No.236098-40-1

CAS: 236098-40-1 Cat. No.: A287678 Molecular Weight: 1909.18

Specifications

Product Name

[Arg14,Lys15]Nociceptin, CAS No.236098-40-1

Biochemical and Physiological Mechanisms

Highly potent and selective NOP receptor agonist (EC50= 1 nM). Displays > 875-fold selectivity over opioid receptors (IC50values are 0.32, 280, > 10000 and 1500 for NOP, μ, δandκreceptors respectively). Longer lasting and 30-fold more potent than nociceptin

Sequence

FGGFTGARKSARKRKNQ

CAS

236098-40-1

Molecule Type

Peptide

Storage and Shipping

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic Polymers
    • Class Polypeptides

• Kingdom: Organic compounds
• Superclass: Organic Polymers
• Class: Polypeptides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Polypeptides
• Alternative Parents: Peptides Arginine and derivatives Phenylalanine and derivatives Glutamine and derivatives Asparagine and derivatives Alpha amino acid amides N-acyl-L-glutamines Serine and derivatives Alanine and derivatives Amphetamines and derivatives Aralkylamines N-acyl amines Primary carboxylic acid amides Amino acids Secondary alcohols Secondary carboxylic acid amides Guanidines Carboximidamides Monocarboxylic acids and derivatives Carboxylic acids Carbonyl compounds Monoalkylamines Primary alcohols Organic oxides Hydrocarbon derivatives Imines
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Polypeptide - Alpha peptide - Arginine or derivatives - Phenylalanine or derivatives - Glutamine or derivatives - Asparagine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - N-acyl-l-glutamine - Alpha-amino acid amide - Serine or derivatives - Alanine or derivatives - N-substituted-alpha-amino acid - Amphetamine or derivatives - Alpha-amino acid or derivatives - Aralkylamine - Fatty acyl - Monocyclic benzene moiety - N-acyl-amine - Fatty amide - Benzenoid - Secondary carboxylic acid amide - Secondary alcohol - Primary carboxylic acid amide - Guanidine - Amino acid or derivatives - Carboxamide group - Amino acid - Carboximidamide - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Carboxylic acid - Hydrocarbon derivative - Imine - Primary aliphatic amine - Alcohol - Organonitrogen compound - Carbonyl group - Organooxygen compound - Organic nitrogen compound - Primary alcohol - Amine - Primary amine - Organic oxygen compound - Organic oxide - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y