Aurothioglucose - Moligand™, 10 mM in DMSO , CAS No.12192-57-3

CAS: 12192-57-3 Cat. No.: A1499268 Molecular Weight: 392.18 EC Number: 235-365-7
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
A1499268-1ml
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$385.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC 50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Names and Identifiers
Isomeric SMILES C([C@@H]1[C@H]([C@@H]([C@H](C(O1)[S-])O)O)O)O.[Au+]
Molecular Weight 392.18
Reaxy-Rn 16127340
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=16127340&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)>107ºC
Citations of This Product
References
1. Cheng Shasha, Dong Xue, Wang Haitao, Song Yukun, Tan Mingqian.  (2023)  High Antibacterial Activity of Spermine Functionalized Carbon Dots and Its Potential Application in Sausage Preservation.  Food and Bioprocess Technology,  16  (12): (3003-3018).  [PMID:] [10.1007/s11947-023-03091-4]
2. Weiwei Ma, Shuangfeng Wan, Chenchen Lin, Xucong Lin, Zenghong Xie.  (2020)  Towards online specific recognition and sensitive analysis of bisphenol A by using AuNPs@aptamer hybrid-silica affinity monolithic column with LC-MS.  TALANTA,      [PMID:32887165] [10.1016/j.talanta.2020.121275]
3. Yamin Liu, Xunjiang Wang, Jiaojiao Wei, Kangning Fu, Yilin Chen, Linnan Li, Zhengtao Wang, Li Yang.  (2024)  Comprehensive Profiling of Amino Acids and Derivatives in Biological Samples: A Robust UHPLC-MS/MS Method for Investigating Acute Lung Injury.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38537486] [10.1016/j.chroma.2024.464816]
4. Feiyun Li, Huinan Liang, Helin Li, Yanjun Tang.  (2025)  Construction of UCST-Responsive Claw-Like Polysulfobetaines for Efficient Capture of Cellulase.  CHEMISTRY-A EUROPEAN JOURNAL,      [PMID:39777747] [10.1002/chem.202404167]
5. Liang Lai, Mengyao Zhang, Tong Li, Jiahuan Qu, Dongsheng Xu, Pei Yu, Zhengjin Jiang.  (2024)  Preparation and evaluation of a piperidinium-sulfonate based zwitterionic monolith for HILIC separation.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38598890] [10.1016/j.chroma.2024.464864]
6. Jinxian Shan, Feiyun Li, Hongming Lou, Yanjun Tang.  (2024)  Valorization of residual lignin from corncob residues into thermosensitive lignin-based “molecular glues” for recycling cellulase.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39251003] [10.1016/j.ijbiomac.2024.135474]
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