Azido-PEG2-amine - ≥98% , CAS No.166388-57-4

CAS: 166388-57-4 Cat. No.: A595143 Molecular Weight: 174.20 EC Number: 812-607-5 PubChem CID: 53401015

GRADE & PURITY ≥98%

Synonyms

ZB0975 | Azido-PEG2-C2-amine | Azido-PEG2-Amine | HY-140213 | 2-(2-(2-azidoethoxy)ethoxy)ethanamine | GS-5982 | SCHEMBL13612332 | 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANAMINE | AB69528 | AMY4540 | MFCD13189985 | N3-PEG2-CH2CH2NH2 | 2-[2-(2-Azidoethoxy)ethoxy]eth

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Azido-PEG2-C2-amine is a PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules. Azido-PEG2-C2-amine is also a non-degradable 2-unit PEG ADC linker that can be used to synthesize antiboy-coupled active molecules (ADCs). Azido-PEG2-C2-amine is a click chemical agent. It contains Azide groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Strain-promoted acetylene-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Specifications

Synonyms

ZB0975 | Azido-PEG2-C2-amine | Azido-PEG2-Amine | HY-140213 | 2-(2-(2-azidoethoxy)ethoxy)ethanamine | GS-5982 | SCHEMBL13612332 | 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANAMINE | AB69528 | AMY4540 | MFCD13189985 | N3-PEG2-CH2CH2NH2 | 2-[2-(2-Azidoethoxy)ethoxy]eth

Specifications & Purity

≥98%

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: C(COCCOCCN=[N+]=[N-])N
• IUPAC Name: 2-[2-(2-azidoethoxy)ethoxy]ethanamine
• InChIKey: ZHWGWSYNZIZTFL-UHFFFAOYSA-N
• INCHI: 1S/C6H14N4O2/c7-1-3-11-5-6-12-4-2-9-10-8/h1-7H2
• Isomeric SMILES: C(COCCOCCN=[N+]=[N-])N
• PubChem CID: 53401015
• Molecular Weight: 174.20

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic 1,3-dipolar compounds
    • Class Allyl-type 1,3-dipolar organic compounds
      • Subclass Azo imides

• Kingdom: Organic compounds
• Superclass: Organic 1,3-dipolar compounds
• Class: Allyl-type 1,3-dipolar organic compounds
• Subclass: Azo imides
• Intermediate Tree Nodes: Not available
• Direct Parent: Azo imides
• Alternative Parents: Azo compounds Dialkyl ethers Organopnictogen compounds Organic salts Monoalkylamines Hydrocarbon derivatives Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Azo compound - Azo imide - Dialkyl ether - Ether - Amine - Organic nitrogen compound - Organic salt - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organic cation - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as azo imides. These are n-Imides of azo compounds, analogous to azoxy compounds, having a delocalized structure.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solubility in Water, DMSO, DMF, DCM
• Sensitivity: Light Sensitive
• Molecular Weight: 174.200 g/mol
• XLogP3: -0.100
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 174.112 Da
• Monoisotopic Mass: 174.112 Da
• Topological Polar Surface Area: 58.800 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 136.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1