Betamethasone solution standard substance in methanol - Moligand™, 100mg/L in methanol , CAS No.378-44-9

CAS: 378-44-9 Cat. No.: B400137 Molecular Weight: 392.46 EC Number: 206-825-4

GRADE & PURITY Moligand™, 100mg/L in methanol

Storage

Room temperature

Specifications

Specifications & Purity

Moligand™, 100mg/L in methanol

Storage

Room temperature

Grade

Moligand™

Product Properties

• ALogP: 1.9

Names and Identifiers

• Isomeric SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
• WGK Germany: 3
• Molecular Weight: 392.46
• Reaxy-Rn: 2341697
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2341697&ln=

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (3 Activities)

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Melt Point(°C): 234-236°C

References

1. Yuan Liang, Zhuolin Li, Jie Zhang, Tiezhu Li, Chengyu Lv.  (2023)  Comparison of the Glucocorticoid Receptor Binding and Agonist Activities of Typical Glucocorticoids: Insights into Their Endocrine Disrupting Effects.  CHEMISTRY & BIODIVERSITY,      [PMID:38129310] [10.1002/cbdv.202301525]

2. Yuan Huang, Zhiqun Zheng, Liying Huang, Hong Yao, Xiao shan Wu, Shaoguang Li, Dandan Lin.  (2017)  Optimization of dispersive liquid-phase microextraction based on solidified floating organic drop combined with high-performance liquid chromatography for the analysis of glucocorticoid residues in food.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:28259095] [10.1016/j.jpba.2017.02.026]

3. Yirong Ma, Min Gong, Xinran Wei, Fan Yang, Yunzhe Li, Guanjun Nan, Zhimin Luo, Aiguo Zeng.  (2025)  A Two-Step Electropolymerization Strategy to Construct an Electrochemical Sensor for Sensitive Detection of Illegal Addition of Betamethasone in Cosmetics.  JOURNAL OF THE ELECTROCHEMICAL SOCIETY,      [PMID:] [10.1149/1945-7111/adbdf3]

4. Chunyi Yu, Xujing Kong, Wenting Li, Boyu Li, Baorong Chen, Mengyao Gao, Susu Cai, Yun Wei.  (2025)  Magnetic molecularly imprinted polymers coupled with UPLC-MS/MS for simultaneous detection of 19 steroid hormones in human plasma.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:39793446] [10.1016/j.chroma.2025.465655]