Carteolol Hydrochloride - 10mM in DMSO , Adrenergic receptor beta antagonist, CAS No.51781-21-6, Adrenergic receptor beta antagonist

CAS: 51781-21-6 Cat. No.: C424441 Formula: C₁₆H₂₄N₂O₃・HCl Peso molecolare: 328.83 Numero EC: 257-415-7

GRADE & PURITY 10mM in DMSO

Synonyms

carteolol hydrochloride|51781-21-6|Carteolol HCl|Arteoptic|Cartrol|Mikelan|Abbott-43326|Ocupress|Endak hydrochloride|Endak|Carbonolol|Endak mite|Abbott 43326|OPC-1085|Carteolol (hydrochloride)|OPC-1085 hydrochloride|EINECS 257-415-7|NSC 300906|NSC-300906|

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Carteolol Hydrochloride is a β-Adrenergic blocker which exhibits antihypertensive, antianginal, antiarrhythmic and antiglaucoma properties.

Specifications

Sinonimi

carteolol hydrochloride | 51781-21-6 | Carteolol HCl | Arteoptic | Cartrol | Mikelan | Abbott-43326 | Ocupress | Endak hydrochloride | Endak | Carbonolol | Endak mite | Abbott 43326 | OPC-1085 | Carteolol (hydrochloride) | OPC-1085 hydrochloride | EINECS 257-415-7 | NSC 300906 | NSC-300906 |

Specifiche e purezza

10mM in DMSO

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

ANTAGONIST

Meccanismo d'azione

Adrenergic receptor beta antagonist

Nomi e identificatori

• Pubchem Sid: 528773769
• Sorrisi canonici: CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O.Cl
• IUPAC Name: 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one;hydrochloride
• InChIKey: FYBXRCFPOTXTJF-UHFFFAOYSA-N
• INCHI: 1S/C16H24N2O3.ClH/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13;/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20);1H
• Isomeri SMILES: CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O.Cl
• CAS alternativo: 51781-06-7
• Peso molecolare: 328.83
• Reaxy-Rn: 5784965
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5784965&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Quinolines and derivatives
      • Subclass Quinolones and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Quinolines and derivatives
• Subclass: Quinolones and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Hydroquinolones
• Alternative Parents: Hydroquinolines Alkyl aryl ethers Benzenoids Secondary carboxylic acid amides Secondary alcohols Lactams Amino acids and derivatives 1,2-aminoalcohols Dialkylamines Azacyclic compounds Organopnictogen compounds Organic oxides Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Tetrahydroquinolone - Tetrahydroquinoline - Alkyl aryl ether - Benzenoid - 1,2-aminoalcohol - Amino acid or derivatives - Carboxamide group - Lactam - Secondary alcohol - Secondary carboxylic acid amide - Azacycle - Secondary amine - Carboxylic acid derivative - Secondary aliphatic amine - Ether - Hydrocarbon derivative - Organic oxygen compound - Organopnictogen compound - Amine - Organonitrogen compound - Organic nitrogen compound - Carbonyl group - Organooxygen compound - Organic oxide - Hydrochloride - Alcohol - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as hydroquinolones. These are compounds containing a hydrogenated quinoline bearing a ketone group.
• External Descriptors: hydrochloride

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

POLK Tbio DNA polymerase kappa (8653 Activities)

Discover Target: POLK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ERG Tbio Transcriptional regulator ERG (5589 Activities)

Discover Target: ERG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Obiettivi associati (non umani)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Sensibilità: Moisture sensitive.
• Punto di fusione (°C): 269-272° C
• Peso molecolare: 328.830 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 328.155 Da
• Monoisotopic Mass: 328.155 Da
• Topological Polar Surface Area: 70.600 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 354.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3