cFMS Receptor Inhibitor II - ≥98% , CAS No.959860-85-6

CAS: 959860-85-6 Cat. No.: C330791 Molecular Weight: 368.4
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
4-(3,4-Dimethylphenylamino)-7-(pyridin-4-yl)quinoline-3-carboxamide | BUN60856
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
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1mg
C330791-1mg
3

$21.90

$32.90
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5mg
C330791-5mg
3

$44.90

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10mg
C330791-10mg
3

$66.90

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25mg
C330791-25mg
2

$134.90

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50mg
C330791-50mg
2

$229.90

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100mg
C330791-100mg
2

$388.90

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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

cFMS Receptor Inhibitor II is a cell-permeable anilinoquinoline compound that acts as a strong, active site-targeting inhibitor of MCSF receptor/cFMS. This inhibitor is much more selective against cFMS-independent growth of NSO cells than cFMS Receptor Inhibitor III . Both cFMS Receptor Inhibitor III and cFMS Receptor Inhibitor II are equally potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells.

Specifications

Synonyms
4-(3, 4-Dimethylphenylamino)-7-(pyridin-4-yl)quinoline-3-carboxamide | BUN60856
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid504769998
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504769998
Canonical SmilesCC1=C(C=C(C=C1)NC2=C3C=CC(=CC3=NC=C2C(=O)N)C4=CC=NC=C4)C
IUPAC Name4-(3,4-dimethylanilino)-7-pyridin-4-ylquinoline-3-carboxamide
InChIKeyBIICXZWYHQOUEQ-UHFFFAOYSA-N
INCHI1S/C23H20N4O/c1-14-3-5-18(11-15(14)2)27-22-19-6-4-17(16-7-9-25-10-8-16)12-21(19)26-13-20(22)23(24)28/h3-13H,1-2H3,(H2,24,28)(H,26,27)
Isomeric SMILES CC1=C(C=C(C=C1)NC2=C3C=CC(=CC3=NC=C2C(=O)N)C4=CC=NC=C4)C
Molecular Weight 368.4
Reaxy-Rn 11293273
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11293273&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassQuinolines and derivatives
SubclassQuinoline carboxamides
Intermediate Tree Nodes Not available
Direct ParentQuinoline-3-carboxamides
Alternative Parents Phenylpyridines  4-aminoquinolines  Pyridinecarboxylic acids and derivatives  o-Xylenes  Aniline and substituted anilines  Aminopyridines and derivatives  Primary aromatic amines  Vinylogous amides  Heteroaromatic compounds  Primary carboxylic acid amides  Amino acids and derivatives  Secondary amines  Azacyclic compounds  Organic oxides  Hydrocarbon derivatives  Organooxygen compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Quinoline-3-carboxamide - 4-phenylpyridine - Aminoquinoline - 4-aminoquinoline - Pyridine carboxylic acid or derivatives - O-xylene - Xylene - Aniline or substituted anilines - Aminopyridine - Monocyclic benzene moiety - Primary aromatic amine - Pyridine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Primary carboxylic acid amide - Carboxamide group - Amino acid or derivatives - Azacycle - Carboxylic acid derivative - Secondary amine - Amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as quinoline-3-carboxamides. These are quinolines in which the quinoline ring system is substituted by one carboxamide group at the 3-position.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CSF1R Tclin Macrophage colony stimulating factor receptor (5179 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
G2206131Certificate of AnalysisApr 03, 2025 C330791
G2206132Certificate of AnalysisApr 03, 2025 C330791
G2206133Certificate of AnalysisApr 03, 2025 C330791
G2206134Certificate of AnalysisApr 03, 2025 C330791
G2206135Certificate of AnalysisApr 03, 2025 C330791
G2206136Certificate of AnalysisApr 03, 2025 C330791
Chemical and Physical Properties
SolubilitySoluble in DMSO
Boil Point(°C)458.3° C at 760 mmHg
Molecular Weight368.400 g/mol
XLogP34.400
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass368.164 Da
Monoisotopic Mass368.164 Da
Topological Polar Surface Area80.900 Ų
Heavy Atom Count28
Formal Charge0
Complexity535.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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