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· · COA & SDS available for every product · Same-day shipping on in-stock items CI 966 hydrochloride - ≥98%(HPLC) , CAS No.110283-66-4
Synonyms
AKOS024456513 | DTXSID30149193 | 1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride | 1-(2-(BIS(4-(TRIFLUOROMETHYL)PHENYL)METHOXY)ETHYL)-1,2,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLIC ACID MONOHYDROCHLOR
Storage
Room temperature,Desiccated
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
AKOS024456513 | DTXSID30149193 | 1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1, 2, 5, 6-tetrahydro-3-pyridinecarboxylic acid hydrochloride | 1-(2-(BIS(4-(TRIFLUOROMETHYL)PHENYL)METHOXY)ETHYL)-1, 2, 5, 6-TETRAHYDRO-3-PYRIDINECARBOXYLIC ACID MONOHYDROCHLOR
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Selective inhibitor of the GABA transporter GAT-1 (IC50values are 0.26 and 1.2μM at cloned human and rat GAT-1 respectively). Displays over 200-fold selectivity over GAT-2 and GAT-3. Centrally active upon systemic administrationin vivo. Anticonvulsive and
Storage
Room temperature, Desiccated
Names and Identifiers Canonical Smiles C1CN(CC(=C1)C(=O)O)CCOC(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C=C3)C(F)(F)F.Cl IUPAC Name 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid;hydrochloride InChIKey NUQWSOWKRTZJTO-UHFFFAOYSA-N INCHI 1S/C23H21F6NO3.ClH/c24-22(25,26)18-7-3-15(4-8-18)20(16-5-9-19(10-6-16)23(27,28)29)33-13-12-30-11-1-2-17(14-30)21(31)32;/h2-10,20H,1,11-14H2,(H,31,32);1H Isomeric SMILES C1CN(CC(=C1)C(=O)O)CCOC(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C=C3)C(F)(F)F.Cl Alternate CAS 110283-79-9 PubChem CID 198692 Molecular Weight 509.87
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Diphenylmethanes Intermediate Tree Nodes Not available Direct Parent Diphenylmethanes Alternative Parents Trifluoromethylbenzenes Alkaloids and derivatives Benzylethers Hydropyridines Trialkylamines Amino acids Azacyclic compounds Monocarboxylic acids and derivatives Carboxylic acids Dialkyl ethers Hydrocarbon derivatives Carbonyl compounds Hydrochlorides Organic oxides Organofluorides Alkyl fluorides Organopnictogen compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents Diphenylmethane - Trifluoromethylbenzene - Benzylether - Alkaloid or derivatives - Hydropyridine - Amino acid or derivatives - Amino acid - Tertiary amine - Tertiary aliphatic amine - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Azacycle - Organoheterocyclic compound - Organohalogen compound - Organic oxide - Organic nitrogen compound - Organopnictogen compound - Amine - Alkyl halide - Alkyl fluoride - Organofluoride - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Hydrochloride - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:ethanol, Max Conc. mg/mL: None, Max Conc. mM: 10; Solvent:DMSO, Max Conc. mg/mL: None, Max Conc. mM: 100 Sensitivity Moisture sensitive Molecular Weight 509.900 g/mol XLogP3 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 10 Rotatable Bond Count 7 Exact Mass 509.119 Da Monoisotopic Mass 509.119 Da Topological Polar Surface Area 49.800 Ų Heavy Atom Count 34 Formal Charge 0 Complexity 643.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
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