Cy5 maleimide - ≥95% , CAS No.1437796-65-0

CAS: 1437796-65-0 Cat. No.: C171350 Molecular Weight: 641.24

GRADE & PURITY ≥95%

Synonyms

1437796-65-0 | 2-(5-(1-(6-((2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-6-oxohexyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1,3,3-trimethyl-3H-indol-1-ium chloride | 6-[(2Z)-3,3-Dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)pe

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Cy5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction.

Specifications

Synonyms

1437796-65-0 | 2-(5-(1-(6-((2-(2, 5-Dioxo-2, 5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-6-oxohexyl)-3, 3-dimethylindolin-2-ylidene)penta-1, 3-dien-1-yl)-1, 3, 3-trimethyl-3H-indol-1-ium chloride | 6-[(2Z)-3, 3-Dimethyl-2-[(2E, 4E)-5-(1, 3, 3-trimethylindol-1-ium-2-yl)pe

Specifications & Purity

≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504773653
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773653
• Canonical Smiles: CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCCCCC(=O)NCCN5C(=O)C=CC5=O)(C)C)C)C.[Cl-]
• IUPAC Name: 6-[(2Z)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]hexanamide;chloride
• InChIKey: IATQCUIJHBSCGA-UHFFFAOYSA-N
• INCHI: 1S/C38H44N4O3.ClH/c1-37(2)28-16-11-13-18-30(28)40(5)32(37)20-8-6-9-21-33-38(3,4)29-17-12-14-19-31(29)41(33)26-15-7-10-22-34(43)39-25-27-42-35(44)23-24-36(42)45;/h6,8-9,11-14,16-21,23-24H,7,10,15,22,25-27H2,1-5H3;1H
• Isomeric SMILES: CC1(C2=CC=CC=C2[N+](=C1/C=C/C=C/C=C\3/C(C4=CC=CC=C4N3CCCCCC(=O)NCCN5C(=O)C=CC5=O)(C)C)C)C.[Cl-]
• Molecular Weight: 641.24
• Reaxy-Rn: 27584855
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27584855&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Indoles and derivatives
      • Subclass Indoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Indoles and derivatives
• Subclass: Indoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 3-alkylindoles
• Alternative Parents: Tertiary alkylarylamines Maleimides Benzenoids N-acyl amines N-substituted carboxylic acid imides Dicarboximides Pyrrolines Amino acids and derivatives Secondary carboxylic acid amides Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Enamines Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic chloride salts Organic cations
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3-alkylindole - Tertiary aliphatic/aromatic amine - Maleimide - Fatty amide - N-acyl-amine - Fatty acyl - Carboxylic acid imide, n-substituted - Benzenoid - Carboxylic acid imide - Dicarboximide - Pyrroline - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Tertiary amine - Carboxylic acid derivative - Enamine - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic salt - Organic chloride salt - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Amine - Organonitrogen compound - Organooxygen compound - Carbonyl group - Organic oxygen compound - Organic cation - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (31 uM, 23 mg/L)
• Sensitivity: light sensitive

References

1. Hang Yu, Rui Feng, Fenglin Chen, Zuodong Wu, Dehai Li, Xue Qiu.  (2024)  Rapid FRET Assay for the Early Detection of Alpha-Synuclein Aggregation in Parkinson’s Disease.  ACS Chemical Neuroscience,      [PMID:38506367] [10.1021/acschemneuro.3c00617]

2. Like Wang, Peiyan Feng, Bo Liu, Xiaonan Huang, Shouwei Yin.  (2025)  A Universal Co-Encapsulation Strategy for Hydrophilic and Hydrophobic Bioactives via Marangoni Effect-Driven Phase-Change Microcapsules.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2025.111522]