Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?
FAQs
Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?
·Reviewed·Published ·Updated ·8 min read
Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?
Because the nitro group on nitrobenzene belongs to a strong passivation group, which has electron absorption induction and conjugation effects, and the density of the π electron cloud on the benzene ring decreases, the Friedel-Crafts acylation reaction will not occur.
Da — when not otherwise indicated, molecular weight units are daltons. Mw — weight-average molecular weight. Mn — number-average molecular weight.
Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Cite this article
Aladdin Scientific. "Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?" Aladdin Knowledge Base, updated Oct 9, 2023. https://www.aladdinsci.com/us_en/faqs/why-does-nitrobenzene-not-undergo-the-friedel-crafts-acylation-reaction-en.html
Was this article helpful?YesNo2 out 5 found this helpful
Related products
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our Cookie Policy.
Shall we send you a message when we have discounts available?
Remind me later
Thank you! Please check your email inbox to confirm.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
