Glycerol Monoleate - ≥90% , CAS No.25496-72-4

CAS: 25496-72-4 Cat. No.: G355281 Molecular Weight: 356.54 EC Number: 247-038-6

GRADE & PURITY ≥90%

Synonyms

1-Oleylglycerol | alpha-Monoolein | Excel O 95F | Oleoyl glycerol | 1-Monooleoyl-rac-glycerol | CHEBI:75342 | Emery oleic acid ester 2221 | Nikkol MGO | rac-1-Monoolein | Monoolein | mono-olein | 1,2,3-Propanetriol mono((Z)-9-octadecenoate) | 2,3-dihydrox

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

1-Oleylglycerol | alpha-Monoolein | Excel O 95F | Oleoyl glycerol | 1-Monooleoyl-rac-glycerol | CHEBI:75342 | Emery oleic acid ester 2221 | Nikkol MGO | rac-1-Monoolein | Monoolein | mono-olein | 1, 2, 3-Propanetriol mono((Z)-9-octadecenoate) | 2, 3-dihydrox

Specifications & Purity

≥90%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥90%

Names and Identifiers

• Canonical Smiles: CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)O
• IUPAC Name: 2,3-dihydroxypropyl (Z)-octadec-9-enoate
• InChIKey: RZRNAYUHWVFMIP-KTKRTIGZSA-N
• INCHI: 1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
• Isomeric SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)O
• Molecular Weight: 356.54
• Reaxy-Rn: 1728976
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728976&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Glycerolipids
      • Subclass Monoradylglycerols
        • Level5 Monoacylglycerols
          • Level6 1-monoacylglycerols

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Glycerolipids
• Subclass: Monoradylglycerols
• Intermediate Tree Nodes: Monoacylglycerols
• Direct Parent: 1-monoacylglycerols
• Alternative Parents: Fatty acid esters Secondary alcohols Carboxylic acid esters 1,2-diols Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: 1-acyl-sn-glycerol - Fatty acid ester - Fatty acyl - 1,2-diol - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Primary alcohol - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Alcohol - Organic oxide - Organooxygen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as 1-monoacylglycerols. These are monoacylglycerols containing a glycerol acylated at the 1-position.
• External Descriptors: Monoacylglycerols

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GPR119 Tclin Glucose-dependent insulinotropic receptor (0 Activities)

Discover Target: GPR119

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

Discover Target: PTGS2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLA2G2A Tchem Phospholipase A2 group IIA (1079 Activities)

Discover Target: PLA2G2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Melt Point(°C): 167.33° C (Predicted)
• Molecular Weight: 356.500 g/mol
• XLogP3: 6.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 19
• Exact Mass: 356.293 Da
• Monoisotopic Mass: 356.293 Da
• Topological Polar Surface Area: 66.800 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 315.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

References

1. Fu Fangqin, Li Xin, Zheng Tengyi, Xia Xiao, Du Minqun, Huang Zhengwei, Huang Ying, Pan Xin, Wu Chuanbin.  (2021)  Stability Evaluation of Lyotropic Liquid Crystalline Precursor for the Co-delivery of Chlorhexidine and Silver Nanoparticles.  AAPS PHARMSCITECH,  22  (7): (1-9).  [PMID:34545436] [10.1208/s12249-021-02102-x]

2. Shangde Sun, Xuebei Hou.  (2019)  A novel caffeic acid-based deep eutectic solvent as caffeoyl donor to enhance glycerol caffeates synthesis.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2018.12.145]

3. Tengyi Zheng, Xintian Huang, Jintian Chen, Disang Feng, Liling Mei, Ying Huang, Guilan Quan, Chune Zhu, Vikramjeet Singh, Hao Ran, Xin Pan, Chuan-Yu Wu, Chuanbin Wu.  (2018)  A liquid crystalline precursor incorporating chlorhexidine acetate and silver nanoparticles for root canal disinfection.  Biomaterials Science,  6  (3): (596-603).  [PMID:29406548] [10.1039/C7BM00764G]

4. Yanru Bao, Shu Ma, Shuning Yuan, Yu Hu, Tao Yang, Hao Jiang.  (2025)  Interactions in starch-lipid complex systems improve 3D printing accuracy and form resistant starch structures: Based on complex properties and molecular simulations.  FOOD CHEMISTRY,      [PMID:41027202] [10.1016/j.foodchem.2025.146526]

5. Qianer Zhu, Xiaoyan Liu, Weiqiang Pan, Xiaoyu Chen, Yuhui Zuo, Xiaoqing Liu, Yuanhong Xu, David Julian McClements, Chengzhen Liu.  (2025)  Fatty acid unsaturation regulates astaxanthin encapsulation in bile salt micelles: Insights into self-assembly mechanisms and molecular interactions.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40997579] [10.1016/j.jcis.2025.139057]

6. Ruoning Zhang, Yanhui Zhang, Tingnan Song, Song Miao, Yanxiang Gao, Like Mao.  (2025)  Shear-responsive oleogels with improved lubrication in oral conditions.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.167053]