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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Golexanolone is a GABA A receptor modulating steroid antagonist. Golexanolone reduces peripheral inflammation and neuroinflammation and improves cognitive and motor function in hyperammonemic rats.
| Canonical Smiles | CC12CCC(CC1CCC3C2CCC4(C3CCC4=NO)C)(C#C)O |
|---|---|
| IUPAC Name | (3S,5S,8R,9S,10S,13S,14S,17E)-3-ethynyl-17-hydroxyimino-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| InChIKey | FFIBGVYTWNPLPN-BZLGYYABSA-N |
| INCHI | 1S/C21H31NO2/c1-4-21(23)12-11-19(2)14(13-21)5-6-15-16-7-8-18(22-24)20(16,3)10-9-17(15)19/h1,14-17,23-24H,5-13H2,2-3H3/b22-18+/t14-,15-,16-,17-,19-,20-,21-/m0/s1 |
| Isomeric SMILES | C[C@]12CC[C@](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]\4([C@H]3CC/C4=N\O)C)(C#C)O |
| Alternate CAS | 2089238-18-4 |
| PubChem CID | 132190533 |
| MeSH Entry Terms | (3S,5S,8R,9S,10S,13S,14S,17E)-3-ethynyl-17-hydroxyimino-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta(a)phenanthren-3-ol;golexanolone;GR3027 |
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