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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Harzianic acid, a tetramic acid derivative, with activity of antimicrobial, antibiofilm formation and biofilm disaggregation. Harzianic acid interferes with biofilm formation by limiting bacterial iron availability. Harzianic acid is also a selective inhibitor of Acetohydroxyacid synthase (AHAS) , the first enzyme in the branched-chain amino acid biosynthetic pathway. Harzianic acid can used for herbicide and fungicide.
| Canonical Smiles | CCCC=CC=CC(=C1C(=O)C(N(C1=O)C)CC(C(C)C)(C(=O)O)O)O |
|---|---|
| IUPAC Name | 2-hydroxy-2-[[(4E)-4-[(2E,4E)-1-hydroxyocta-2,4-dienylidene]-1-methyl-3,5-dioxopyrrolidin-2-yl]methyl]-3-methylbutanoic acid |
| InChIKey | FQSWTHMMNDRFAI-RFJZBCCMSA-N |
| INCHI | 1S/C19H27NO6/c1-5-6-7-8-9-10-14(21)15-16(22)13(20(4)17(15)23)11-19(26,12(2)3)18(24)25/h7-10,12-13,21,26H,5-6,11H2,1-4H3,(H,24,25)/b8-7+,10-9+,15-14+ |
| Isomeric SMILES | CCC/C=C/C=C/C(=C\1/C(=O)C(N(C1=O)C)CC(C(C)C)(C(=O)O)O)/O |
| Alternate CAS | 157148-06-6 |
| PubChem CID | 54691490 |
| MeSH Entry Terms | harzianic acid |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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