IDT307 - ≥99% , CAS No.1141-41-9

CAS: 1141-41-9 Cat. No.: I647368 Molecular Weight: 340.21 EC Number: 806-006-7 PubChem CID: 13227270

GRADE & PURITY ≥99%

Synonyms

4-(4-(Dimethylamino)phenyl)-1-methylpyridin-1-ium iodide | AS-16794 | SR-01000395352 | N,N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline;iodide | 4-[4-(Dimethylamino)phenyl]-1-methylpyridin-1-ium iodide | 4-(4-(dimethylamino)phenyl)-1-methylpyridinium io

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

Overview

IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+).

In Vitro

IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine. IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Synonyms

4-(4-(Dimethylamino)phenyl)-1-methylpyridin-1-ium iodide | AS-16794 | SR-01000395352 | N, N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline;iodide | 4-[4-(Dimethylamino)phenyl]-1-methylpyridin-1-ium iodide | 4-(4-(dimethylamino)phenyl)-1-methylpyridinium io

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+).

Storage

Store at 2-8°C, Protected from light, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: C[N+]1=CC=C(C=C1)C2=CC=C(C=C2)N(C)C.[I-]
• IUPAC Name: N,N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline;iodide
• InChIKey: CAMWVBRDIKKGII-UHFFFAOYSA-M
• INCHI: 1S/C14H17N2.HI/c1-15(2)14-6-4-12(5-7-14)13-8-10-16(3)11-9-13;/h4-11H,1-3H3;1H/q+1;/p-1
• Isomeric SMILES: C[N+]1=CC=C(C=C1)C2=CC=C(C=C2)N(C)C.[I-]
• PubChem CID: 13227270
• Molecular Weight: 340.21

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyridines and derivatives
      • Subclass Phenylpyridines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyridines and derivatives
• Subclass: Phenylpyridines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylpyridines
• Alternative Parents: Dialkylarylamines Aniline and substituted anilines N-methylpyridinium compounds Pyridinium derivatives Heteroaromatic compounds Azacyclic compounds Organic iodide salts Hydrocarbon derivatives Organic cations
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 4-phenylpyridine - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - N-methylpyridinium - Monocyclic benzene moiety - Pyridinium - Benzenoid - Heteroaromatic compound - Tertiary amine - Azacycle - Organic salt - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organonitrogen compound - Organic iodide salt - Organic cation - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as phenylpyridines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyridine ring through a CC or CN bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: DMSO : 62.5 mg/mL (183.72 mM; Need ultrasonic)
• Molecular Weight: 340.200 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 340.044 Da
• Monoisotopic Mass: 340.044 Da
• Topological Polar Surface Area: 7.100 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 199.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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