Derived from Streptomyces kanamycin, ≥ 670IU/mg for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Description
Chemical structure: aminoglycosideKanamycin sulfate is a broad spectrum minoglycoside-antibiotic It is used as an additive in culture media for the isolation of group DStreptococcion Kanamycin Esculin Azide Agar (Mossel et al.) or for selection of transformed plant cells containing the neomycin phosphotransferase (for kanamycin resistance); on a kanamycin-medium. Kanamycin has been used for electrophysiological recordings of outer hair cells and inner hair cells. It is used to inhibit shoot regeneration from Siberian Elmleaf explants. It is recommended for use in cell culture applications at 100 mg/mL.
Preparation instructions
Kanamycin sulfate is soluble in water at 10 mg/mL, yielding a clear solution. It is practically insoluble in alcohol, acetone, chloroform, ether and ethyl acetate. A 1% solution in water has a pH of 6.5 to 8.5. Sterile solutions can be prepared by a sterile filtration, through a .2μm filter.Kanamycin acid sulfate is prepared by solubilizing kanamycin sulfate in dilute sulfuric acid and drying. The sulfate content is approximately 25%.
| Canonical Smiles | OS(O)(=O)=O.OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O |
|---|---|
| IUPAC Name | (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid |
| InChIKey | OGTKIXVMLDAMNU-KNQICTBBSA-N |
| INCHI | 1S/C18H36N4O11.2H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;2*1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;2*(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;;/m1../s1 |
| Isomeric SMILES | C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N.OS(=O)(=O)O.OS(=O)(=O)O |
| WGK Germany | 3 |
| Molecular Weight | 680.66 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Carbohydrates and carbohydrate conjugates |
| Intermediate Tree Nodes | Aminosaccharides - Aminoglycosides - Aminocyclitol glycosides - 2-deoxystreptamine aminoglycosides |
| Direct Parent | 4,6-disubstituted 2-deoxystreptamines |
| Alternative Parents | O-glycosyl compounds Aminocyclitols and derivatives Cyclohexanols Cyclohexylamines Organic sulfuric acids Monosaccharides Oxanes 1,2-aminoalcohols Polyols Acetals Oxacyclic compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Primary alcohols |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | 4,6-disubstituted 2-deoxystreptamine - Glycosyl compound - O-glycosyl compound - Aminocyclitol or derivatives - Cyclohexanol - Cyclohexylamine - Sulfuric acid - Cyclitol or derivatives - Monosaccharide - Oxane - Cyclic alcohol - Organic sulfuric acid or derivatives - 1,2-aminoalcohol - Secondary alcohol - Polyol - Acetal - Organoheterocyclic compound - Oxacycle - Organonitrogen compound - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Primary amine - Organopnictogen compound - Organic nitrogen compound - Amine - Alcohol - Primary alcohol - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as 4,6-disubstituted 2-deoxystreptamines. These are 2-deoxystreptamine aminoglycosides that a glycosidically linked to a pyranose of furanose unit at the C4- and C6-positions. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 L2522530 | Certificate of Analysis | Dec 05, 2025 | K475878 |
| L2522531 | Certificate of Analysis | Dec 05, 2025 | K475878 |
| L2522532 | Certificate of Analysis | Dec 05, 2025 | K475878 |
| L2522533 | Certificate of Analysis | Dec 05, 2025 | K475878 |
| Solubility | H2O: 10mg/mL |
|---|---|
| Molecular Weight | 680.700 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 15 |
| Hydrogen Bond Acceptor Count | 23 |
| Rotatable Bond Count | 6 |
| Exact Mass | 680.173 Da |
| Monoisotopic Mass | 680.173 Da |
| Topological Polar Surface Area | 449.000 Ų |
| Heavy Atom Count | 43 |
| Formal Charge | 0 |
| Complexity | 720.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 15 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 3 |
| 1. Yizhen Zhang, Yu-Cai He, Cuiluan Ma. (2024) Efficient synthesis of vanillylamine through bioamination of lignin-derived vanillin by recombinant E. coli containing ω-transaminase from Caulobacter sp. D5 in dimethyl sulfoxide-water. BIORESOURCE TECHNOLOGY, [PMID:39321936] [10.1016/j.biortech.2024.131526] |
| 2. Di Junhua, Qin Lizhen, He Yu-Cai. (2022) Valorization of biomass to furfuryl alcohol via chemoenzymatic cascade catalysis by deep eutectic solvent-silica heterogeneous catalyst and reductase biocatalyst in the aqueous system. Biomass Conversion and Biorefinery, 13 (17): (15837-15844). [PMID:] [10.1007/s13399-021-02171-9] |
| 3. Lijuan Yang, Lumin Zeng, Yongqing Tao, Dandan Wang, Kailian Zhang, Meng Tian, Zhining Xia, Die Gao. (2021) Galli Gigerii Endothelium Corneum derived fluorescent carbon dots and their application as sensing platform for nitroimidazoles and cell imaging. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2021.107089] |
