L-Phenylalanine-d - Moligand™, 10 mM in DMSO , CAS No.56253-90-8

CAS: 56253-90-8 Cat. No.: L1499764 Molecular Weight: 170.22

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

L-Phenylalanine-d 5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Protected from light, Argon charged, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

ANTAGONIST

Names and Identifiers

• Isomeric SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])C[C@@H](C(=O)O)N)[2H])[2H]
• Alternate CAS: 63-91-2（unlabelled）
• Molecular Weight: 170.22
• Reaxy-Rn: 1910407
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1910407&ln=

Chemical and Physical Properties

• Melt Point(°C): 243-246° C

References

1. Ningbo Geng, Yun Luo, Rong Cao, Xiaoyao Song, Fang Li, Feidi Wang, Yufeng Gong, Liguo Xing, Haijun Zhang, Jiping Chen.  (2020)  Effect of short-chain chlorinated paraffins on metabolic profiling of male SD rats.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:33182165] [10.1016/j.scitotenv.2020.141404]