L-Serine - PharmPure™, USP, JP, Ph.Eur. , CAS No.56-45-1

CAS: 56-45-1 Cat. No.: GMP1527800 Molecular Weight: 105.09 Beilstein Registry Number: 1721404 EC Number: 200-274-3

GRADE & PURITY PharmPure™, USP, JP, Ph.Eur.

Storage

Room temperature

Shipped In

Normal

Overview

L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.

Specifications

Specifications & Purity

PharmPure™, USP, JP, Ph.Eur.

Biochemical and Physiological Mechanisms

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.Precursor of glycine by serine hydroxymethyltransferase.

Storage

Room temperature

Shipped In

Normal

Grade

JP, Ph.Eur., PharmPure™, USP

Names and Identifiers

• Canonical Smiles: C(C(C(=O)O)N)O
• IUPAC Name: (2S)-2-amino-3-hydroxypropanoic acid
• InChIKey: MTCFGRXMJLQNBG-REOHCLBHSA-N
• INCHI: 1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
• Isomeric SMILES: C([C@@H](C(=O)O)N)O
• WGK Germany: 1
• RTECS: VT8100000
• Molecular Weight: 105.09
• Beilstein: 1721404
• Reaxy-Rn: 1721402
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721402&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Serine and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Serine and derivatives
• Alternative Parents: L-alpha-amino acids Beta hydroxy acids and derivatives Amino acids Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Serine or derivatives - Alpha-amino acid - L-alpha-amino acid - Beta-hydroxy acid - Hydroxy acid - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Alcohol - Primary amine - Primary alcohol - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Primary aliphatic amine - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Organic nitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as serine and derivatives. These are compounds containing serine or a derivative thereof resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Common amino acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: H2O: 50mg/mL
• Specific Rotation[α]: 15° (C=10,HCl(1+5))
• Melt Point(°C): 228°C(dec.)(lit.)
• Molecular Weight: 105.090 g/mol
• XLogP3: -3.100
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 105.043 Da
• Monoisotopic Mass: 105.043 Da
• Topological Polar Surface Area: 83.600 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 72.600
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1