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· · COA & SDS Disponibile per ogni prodotto · Spedizione lo stesso giorno su articoli in magazzino LY2562175 - ≥99% , Bile acid receptor FXR agonist, CAS No.1103500-20-4, Bile acid receptor FXR agonist
Synonyms
SB19684 | 1103500-20-4 | AKOS040741985 | UNII-VVA2ZDV3LX | MS-29957 | TERN-101 | AC-36270 | RPVDFHPBGBMWID-UHFFFAOYSA-N | SCHEMBL1097262 | VVA2ZDV3LX | 6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-ca
Shipped In
Ice chest + Ice pads
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Why this grade ≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica LY2562175 is a potent and selective FXR agonist, with an EC50 of 193 nM.
Targets
human FXR (cell-based cotransfection assay) 193 nM(EC50)
Specifications Sinonimi
SB19684 | 1103500-20-4 | AKOS040741985 | UNII-VVA2ZDV3LX | MS-29957 | TERN-101 | AC-36270 | RPVDFHPBGBMWID-UHFFFAOYSA-N | SCHEMBL1097262 | VVA2ZDV3LX | 6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-ca
Meccanismi biochimici e fisiologici
LY2562175 is a potent and selective agonist of FXR. LY2562175 promotes transcriptional activation of human FXR in a cell-based cotransfection assay with EC50 of 193 nM.
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Meccanismo d'azione
Bile acid receptor FXR agonist
Proprietà del prodotto Nomi e identificatori Pubchem Sid 528765337 Sorrisi canonici CN1C=C(C2=C1C=C(C=C2)N3CCC(CC3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)C(=O)O IUPAC Name 6-[4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]piperidin-1-yl]-1-methylindole-3-carboxylic acid InChIKey RPVDFHPBGBMWID-UHFFFAOYSA-N INCHI 1S/C28H27Cl2N3O4/c1-32-14-20(28(34)35)19-8-7-17(13-24(19)32)33-11-9-18(10-12-33)36-15-21-26(31-37-27(21)16-5-6-16)25-22(29)3-2-4-23(25)30/h2-4,7-8,13-14,16,18H,5-6,9-12,15H2,1H3,(H,34,35) Isomeri SMILES CN1C=C(C2=C1C=C(C=C2)N3CCC(CC3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)C(=O)O Peso molecolare 540.44 Reaxy-Rn 20184274 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20184274&ln=
Documentazione 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Indoles and derivatives Subclass Indolecarboxylic acids and derivatives Intermediate Tree Nodes Not available Direct Parent Indolecarboxylic acids and derivatives Alternative Parents N-alkylindoles Indoles Pyrrole carboxylic acids 5-cyclopropylisoxazoles Dichlorobenzenes Dialkylarylamines Piperidines N-methylpyrroles Aryl chlorides Vinylogous amides Heteroaromatic compounds Amino acids Oxacyclic compounds Dialkyl ethers Carboxylic acids Azacyclic compounds Hydrocarbon derivatives Organic oxides Organochlorides Molecular Framework Aromatic heteropolycyclic compounds Substituents Indolecarboxylic acid derivative - N-alkylindole - Indole - 5-cyclopropylisoxazole - Cyclopropylisoxazole - 1,3-dichlorobenzene - Pyrrole-3-carboxylic acid - Pyrrole-3-carboxylic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Halobenzene - Chlorobenzene - N-methylpyrrole - Aryl chloride - Aryl halide - Piperidine - Substituted pyrrole - Monocyclic benzene moiety - Benzenoid - Azole - Heteroaromatic compound - Pyrrole - Isoxazole - Vinylogous amide - Amino acid or derivatives - Amino acid - Tertiary amine - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Azacycle - Dialkyl ether - Ether - Organic oxygen compound - Organic nitrogen compound - Amine - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Organonitrogen compound - Organochloride - Organohalogen compound - Aromatic heteropolycyclic compound Descrizione This compound belongs to the class of organic compounds known as indolecarboxylic acids and derivatives. These are compounds containing a carboxylic acid group (or a derivative thereof) linked to an indole. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Solubilità Solubility (25°C) In vitro DMSO: 100 mg/mL (185.03 mM); Ethanol: 1.5 mg/mL (2.77 mM); Water: Insoluble; Peso molecolare 540.400 g/mol XLogP3 5.500 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 7 Exact Mass 539.138 Da Monoisotopic Mass 539.138 Da Topological Polar Surface Area 80.700 Ų Heavy Atom Count 37 Formal Charge 0 Complexity 800.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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