N-Acetyl-L-tryptophan - Moligand™, 10 mM in DMSO , CAS No.1218-34-4

CAS: 1218-34-4 Cat. No.: N1500421 Molecular Weight: 246.26 Beilstein Registry Number: 22(3/4)6781 EC Number: 214-935-9
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
N1500421-1ml
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$28.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor ( NK-1R ), disrupting the binding of substance P (SP) to NK-1R . This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c ( Cytochrome c ), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1 . N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Names and Identifiers
Isomeric SMILES CC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O
WGK Germany 2
RTECS YN6160000
Molecular Weight 246.26
Beilstein 22(3/4)6781
Reaxy-Rn 487262
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=487262&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Specific Rotation[α]26 ° (C=1, 1mol/L NaOH)
Melt Point(°C)186°C
Citations of This Product
References
1. Xiuzhen Qiu, Weimao Chen, Yiling Luo, Yulin Wang, Yanlian Wang, Huishi Guo.  (2019)  Highly sensitive α-amanitin sensor based on molecularly imprinted photonic crystals.  ANALYTICA CHIMICA ACTA,      [PMID:31735207] [10.1016/j.aca.2019.09.066]
2. Qici Wu, Qilei Zhang, Shiwen Xu, Chengtong Ge, Shanjing Yao, Dongqiang Lin.  (2017)  Preparation and evaluation of mixed-mode resins with tryptophan analogues as functional ligands for human serum albumin separation.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2016.12.010]
3. Yuting Li, Xiaotong Li, Jinshun Ye, Zhenzhao Weng, Xiaozhen Liu, Fengyuan Liu, Jingkun Yan, Lin Li.  (2024)  Reactivity of amino acid residues towards 4-methylbenzoquinone: Effect on the site-specificity of quinone-protein reaction.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2024.116217]
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