Nα-Fmoc-6-hydroxynorleucine - ≥95% , CAS No.374899-60-2

CAS: 374899-60-2 Cat. No.: N346021 Molecular Weight: 369.41 PubChem CID: 51340510
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
Fmoc-L-Nle(6-OH)-OH | (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-hydroxyhexanoic acid | (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-hydroxyhexanoic acid
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100mg
N346021-100mg
1

$103.90

$155.90
Save $52.00 (33.35%)
250mg
N346021-250mg
1

$125.90

$188.90
Save $63.00 (33.35%)
1g
N346021-1g
1

$415.90

$623.90
Save $208.00 (33.34%)
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Na-Fmoc-6-hydroxynorleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for enhanced stability and solubility, making it an ideal choice for researchers focused on developing complex peptide sequences. The hydroxyl group at the 6-position further enhances its reactivity, facilitating the incorporation of this amino acid into various peptide chains.

Specifications

Synonyms
Fmoc-L-Nle(6-OH)-OH | (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-hydroxyhexanoic acid | (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-hydroxyhexanoic acid
Specifications & Purity
≥95%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%
Names and Identifiers
Canonical SmilesC1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCCCO)C(=O)O
IUPAC Name(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-hydroxyhexanoic acid
InChIKeyRLKMUBZYLZBKMO-IBGZPJMESA-N
INCHI1S/C21H23NO5/c23-12-6-5-11-19(20(24)25)22-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19,23H,5-6,11-13H2,(H,22,26)(H,24,25)/t19-/m0/s1
Isomeric SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CCCCO)C(=O)O
PubChem CID 51340510
Molecular Weight 369.41

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassFluorenes
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentFluorenes
Alternative Parents Alpha amino acids and derivatives  Medium-chain hydroxy acids and derivatives  Medium-chain fatty acids  Hydroxy fatty acids  Amino fatty acids  Carbamate esters  Monocarboxylic acids and derivatives  Carboxylic acids  Primary alcohols  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents Fluorene - Alpha-amino acid or derivatives - Medium-chain hydroxy acid - Medium-chain fatty acid - Amino fatty acid - Hydroxy fatty acid - Fatty acyl - Fatty acid - Carbamic acid ester - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Primary alcohol - Hydrocarbon derivative - Organic oxide - Organic nitrogen compound - Alcohol - Carbonyl group - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Aromatic homopolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
A2513140Certificate of AnalysisJan 04, 2025 N346021
A2513141Certificate of AnalysisJan 04, 2025 N346021
A2513142Certificate of AnalysisJan 04, 2025 N346021
A2513158Certificate of AnalysisJan 04, 2025 N346021
A2513159Certificate of AnalysisJan 04, 2025 N346021
Chemical and Physical Properties
Molecular Weight369.400 g/mol
XLogP33.100
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count9
Exact Mass369.158 Da
Monoisotopic Mass369.158 Da
Topological Polar Surface Area95.900 Ų
Heavy Atom Count27
Formal Charge0
Complexity489.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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