Patisiran sodium - ≥96% , CAS No.1386913-72-9

CAS: 1386913-72-9 Cat. No.: P646702 Molecular Weight: 13427.10 (AS: 6661.3; SS: 6765.8)

GRADE & PURITY ≥96%

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Patisiran sodium is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran sodium specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran sodium can be used for the research of hereditary TTR amyloidosis .

In Vitro

Patisiran sodium causes TTR degradation (via RNA interference) and subsequently a reduction in serum TTR protein levels and tissue TTR protein deposits by specifically binding to a genetically conserved sequence in the 3' untranslated region of mutant and wild-type transthyretin (TTR) messenger RNA. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Specifications & Purity

≥96%

Biochemical and Physiological Mechanisms

帕替西兰钠是一种双链小干扰 RNA，靶向转甲状腺素（TTR）信使 RNA 中的一个序列。帕替西兰钠能特异性抑制突变型和野生型 TTR 的肝脏合成。帕替西兰钠可用于

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥96%

Names and Identifiers

• Canonical Smiles: [Patisiran (sodium)]
• Molecular Weight: 13427.10 (AS: 6661.3; SS: 6765.8)

Chemical and Physical Properties

• Solubility: H2O : 33.33 mg/mL (Need ultrasonic)