Determine the necessary mass, volume, or concentration for preparing a solution.
≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 16 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488187504 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488187504 |
| Canonical Smiles | C(=O)(C(C(F)(F)F)(OC(C(C(F)(F)F)(F)F)(F)F)F)O |
| IUPAC Name | 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid |
| InChIKey | CSEBNABAWMZWIF-UHFFFAOYSA-N |
| INCHI | 1S/C6HF11O3/c7-2(1(18)19,4(10,11)12)20-6(16,17)3(8,9)5(13,14)15/h(H,18,19) |
| Isomeric SMILES | C(=O)(C(C(F)(F)F)(OC(C(C(F)(F)F)(F)F)(F)F)F)O |
| PubChem CID | 114481 |
| Molecular Weight | 330.06 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Alpha-halocarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Alpha-halocarboxylic acids |
| Alternative Parents | Monocarboxylic acids and derivatives Carboxylic acids Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Alpha-halocarboxylic acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organofluoride - Organohalogen compound - Carbonyl group - Alkyl halide - Alkyl fluoride - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as alpha-halocarboxylic acids. These are carboxylic acids containing a halogen atom bonded to the alpha carbon atom. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 25, 2026 | P302398 | |
| Certificate of Analysis | Apr 25, 2026 | P302398 | |
| Certificate of Analysis | Apr 25, 2026 | P302398 | |
| Certificate of Analysis | Apr 25, 2026 | P302398 | |
| Certificate of Analysis | Apr 25, 2026 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jul 03, 2025 | P302398 | |
| Certificate of Analysis | Jun 10, 2025 | P302398 | |
| Certificate of Analysis | Jul 23, 2024 | P302398 | |
| Certificate of Analysis | Jul 23, 2024 | P302398 | |
| Certificate of Analysis | Jul 23, 2024 | P302398 | |
| Certificate of Analysis | Jul 23, 2024 | P302398 | |
| Certificate of Analysis | Jul 23, 2024 | P302398 | |
| Certificate of Analysis | Jul 23, 2024 | P302398 | |
| Certificate of Analysis | May 06, 2024 | P302398 | |
| Certificate of Analysis | Nov 28, 2023 | P302398 | |
| Certificate of Analysis | Nov 28, 2023 | P302398 | |
| Certificate of Analysis | Nov 28, 2023 | P302398 | |
| Certificate of Analysis | Nov 28, 2023 | P302398 | |
| Certificate of Analysis | Nov 28, 2023 | P302398 | |
| Certificate of Analysis | Jun 30, 2022 | P302398 | |
| Certificate of Analysis | Jun 30, 2022 | P302398 | |
| Certificate of Analysis | Jun 30, 2022 | P302398 | |
| Certificate of Analysis | Mar 19, 2021 | P302398 | |
| Certificate of Analysis | Mar 19, 2021 | P302398 | |
| Certificate of Analysis | Mar 19, 2021 | P302398 |
| Boil Point(°C) | 60°/10mm |
|---|---|
| Molecular Weight | 330.050 g/mol |
| XLogP3 | 3.600 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 4 |
| Exact Mass | 329.975 Da |
| Monoisotopic Mass | 329.975 Da |
| Topological Polar Surface Area | 46.500 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 383.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Shi-Ya Peng, Ya-Di Yang, Rong Tian, Naihao Lu. (2024) Critical new insights into the interactions of hexafluoropropylene oxide-dimer acid (GenX or HFPO-DA) with albumin at molecular and cellular levels. Journal of Environmental Sciences, [PMID:39181681] [10.1016/j.jes.2024.02.011] |
| 2. Jinjing Huang, Kaixing Fu, Zhuoya Fang, Jinming Luo. (2024) Enhanced selective removal of PFAS at trace level using quaternized cellulose-functionalized polymer resin: Performance and mechanism. WATER RESEARCH, [PMID:39674139] [10.1016/j.watres.2024.122937] |
| 3. Yang Wang, Hui Li, Ji Li, Lina Zhou, Chunkai Feng, Guangwei Liu, Jianzhi Wang, Chen Hou. (2025) Fluorophilic N, S self-doped porous carbon electrodes derived from biomass gelatin for electro-Fenton degradation of GenX. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2025.115386] |
| 4. Dengdiao Yao, Jian Shao, Dantong Jia, Weiling Sun. (2024) Immunotoxicity of legacy and alternative per- and polyfluoroalkyl substances on zebrafish larvae. ENVIRONMENTAL POLLUTION, [PMID:38977121] [10.1016/j.envpol.2024.124511] |
| 5. Jianglin Hu, Jiayin Dai, Nan Sheng. (2024) Kynurenic Acid Plays a Protective Role in Hepatotoxicity Induced by HFPO-DA in Male Mice. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:38228288] [10.1021/acs.est.3c08033] |
| 6. Mei-Ling Le, Jia-Yu Xue, Li-Hai Wu, Xin-Yuan Zhao, Jing Ding, Yang-Yang Yuan, Yi-Qi Wan, Da-Lei Zhang. (2025) Hexafluoropropylene Oxide Homologues, the Novel Alternatives to PFOA, Induce Mitochondrial Dysfunction and Cytotoxicity in Leydig Cells through Disrupting SIRT1/PGC-1α Signaling Pathway. TOXICOLOGY, [PMID:40972997] [10.1016/j.tox.2025.154282] |
| 7. Juan Li, Boqiang Li, Huimei Pan, Yiya Wei, Yang Yang, Nan Xu, Baiyang Chen, Madjid Mohseni, Ehsan Banayan Esfahani. (2022) Total organic fluorine (TOF) analysis by completely converting TOF into fluoride with vacuum ultraviolet. JOURNAL OF HAZARDOUS MATERIALS, [PMID:35236042] [10.1016/j.jhazmat.2022.128389] |
| 8. Boxuan Yang, Yuxin Zeng, Tao Guo, Yuanzhong Lin, Lifeng Yin, Qingsong Hua. (2025) Electrocatalytic removal of Hexafluoropropylene oxide dimer acid (HFPO-DA) in water: “Buttering on both Sides”. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2025.133001] |
| 9. Mei-Ling Le, Yi-Qi Wan, Jia-Yu Xue, Shi-Yi Deng, Bin-Hui Wang, Li-Hai Wu, Hou-Peng Wang, Yang-Yang Yuan, Xiao-Dong Kuang, Tao Luo, Da-Lei Zhang. (2025) HFPO homologues, the novel alternatives to PFOA, impair male reproduction in mice through inducing mitochondrial dysfunction. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:40460775] [10.1016/j.ecoenv.2025.118435] |
| 10. Yuanyuan Wu, Weiqiang Sun, Xiyue Liu, Zhonghua Fan, Lin Cheng, Ying Yang, Li Wang, Hui Liu. (2025) PFOA and its substitutes disrupt fatty acid metabolism and impair erythrocyte homeostasis in zebrafish. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:40555089] [10.1016/j.ecoenv.2025.118546] |
| 11. Shiqi Xiao, Yao Liu, Sheng Ding, Dianxiang Lu, Jin Yang, Xiangke Niu, Xin Qi, Jiawei Wei. (2025) GenX-loaded polystyrene microplastics exacerbate intestinal injury in mice via barrier impairment and microbial dysregulation. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2025.119812] |
| 12. Yangyang Yuan, Binhui Wang, Yuyu Fan, Meiling Le, Lihai Wu, Shiyi Deng, Jian Huang, Dalei Zhang. (2025) Comparative assessment of female reproductive toxicity from PFOA and its alternative GenX in mice and human granulosa cells. TOXICOLOGY AND APPLIED PHARMACOLOGY, [PMID:41232729] [10.1016/j.taap.2025.117639] |
| 13. Qinyu Wang, Zhonghao Chen, Xinrui Li, Kemeng Wang, Ke Wang, Yinjuan Chen, Zhugen Yang, Yanyan Zhang, Lei Wang. (2025) Scalable and Sustainable Cellulose Xerogels for High-Capacity Enrichment of Per- and polyfluoroalkyl Substances. WATER RESEARCH, [PMID:41455428] [10.1016/j.watres.2025.125258] |
| 14. Yuntao Qi, Qianyue Yin, Penghang Ni, Wansong Zong, Qigui Niu, Rutao Liu. (2025) Synergistic Effect of Nanoplastics and GenX on Human Serum Albumin: The Role of Protein Corona Formation and Co-Adsorption. Toxics, 14 (1): [PMID:41600561] [10.3390/toxics14010012] |
| 15. Zhen Ren, Zimou Feng, Huaxing Liang, Zhiyang Zhu, Yi Yang, Xinglin Lu. (2026) In Situ Surfactant-Assisted Assembly for Efficient Removal of PFAS by Low-Pressure Ultrafiltration Membrane Process. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:41489990] [10.1021/acs.est.5c13478] |
| 16. Ding Hongran, Slack Maya, McClure Holly, Gu Wen, Gu Helene, Kappes Ferdinand, Schultz Thomas F., Somarelli Jason A., Tsigkou Anastasia. (2026) Exposure to PFOA and GenX elicits cell typespecific impacts on p53 and TGF-β signaling pathways. MOLECULAR BIOLOGY REPORTS, 53 (1): (440). [PMID:41758393] [10.1007/s11033-026-11571-x] |