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· · COA & SDS available for every product · Same-day shipping on in-stock items Ponesimod - Moligand™, ≥97% , Sphingosine 1-phosphate receptor Edg-1 agonist, CAS No.854107-55-4, Sphingosine 1-phosphate receptor Edg-1 agonist
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97% Synonyms
BP175283 | Ponesimod,ACT-128800 | 4-Thiazolidinone, 5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylene]-3-(2-methylphenyl)-2-(propylimino)-, (2Z,5Z)- | 5G7AKV2MKP | PONESIMOD [USAN] | STK374497 | AMY23424 | (2Z,5Z)-5-(3-Chloro-4-((R)-2,3-dihydroxy
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
BP175283 | Ponesimod, ACT-128800 | 4-Thiazolidinone, 5-[[3-chloro-4-[(2R)-2, 3-dihydroxypropoxy]phenyl]methylene]-3-(2-methylphenyl)-2-(propylimino)-, (2Z, 5Z)- | 5G7AKV2MKP | PONESIMOD [USAN] | STK374497 | AMY23424 | (2Z, 5Z)-5-(3-Chloro-4-((R)-2, 3-dihydroxy
Specifications & Purity
Moligand™, ≥97%
Biochemical and Physiological Mechanisms
Ponesimod is a potent agonist of sphingosine-1-phophate receptor.\xa0(S1P 1 /EDG-1; IC 50 s = 6, >10, 000, 2, 068, 1, 956, and 142 nM for S1P 1 -S1P 5 , respectively, in a radioligand binding assay). Selectively activates S1P 1 in a GTPγS assay (EC 50 s = 5.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Sphingosine 1-phosphate receptor Edg-1 agonist
Product Properties Names and Identifiers Pubchem Sid 504766343 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504766343 Canonical Smiles CCCN=C1N(C(=O)C(=CC2=CC(=C(C=C2)OCC(CO)O)Cl)S1)C3=CC=CC=C3C IUPAC Name (5Z)-5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylidene]-3-(2-methylphenyl)-2-propylimino-1,3-thiazolidin-4-one InChIKey LPAUOXUZGSBGDU-ULCCENQXSA-N INCHI 1S/C23H25ClN2O4S/c1-3-10-25-23-26(19-7-5-4-6-15(19)2)22(29)21(31-23)12-16-8-9-20(18(24)11-16)30-14-17(28)13-27/h4-9,11-12,17,27-28H,3,10,13-14H2,1-2H3/b21-12-,25-23?/t17-/m1/s1 Isomeric SMILES CCCN=C1N(C(=O)/C(=C/C2=CC(=C(C=C2)OC[C@@H](CO)O)Cl)/S1)C3=CC=CC=C3C PubChem CID 11363176 Molecular Weight 460.974
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Phenol ethers Subclass Not available Intermediate Tree Nodes Not available Direct Parent Phenol ethers Alternative Parents Phenoxy compounds Toluenes Alkyl aryl ethers Chlorobenzenes Aryl chlorides Thiazolidines Secondary alcohols 1,2-diols Isothioureas Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Carboxylic acids and derivatives Hydrocarbon derivatives Carbonyl compounds Organic oxides Organochlorides Organonitrogen compounds Primary alcohols Molecular Framework Aromatic heteromonocyclic compounds Substituents Phenoxy compound - Phenol ether - Alkyl aryl ether - Halobenzene - Chlorobenzene - Toluene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Thiazolidine - 1,2-diol - Isothiourea - Secondary alcohol - Propargyl-type 1,3-dipolar organic compound - Carboxylic acid derivative - Organic 1,3-dipolar compound - Ether - Organoheterocyclic compound - Azacycle - Organic nitrogen compound - Organohalogen compound - Organochloride - Organonitrogen compound - Organooxygen compound - Carbonyl group - Primary alcohol - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Alcohol - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 461.000 g/mol XLogP3 4.600 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 8 Exact Mass 460.122 Da Monoisotopic Mass 460.122 Da Topological Polar Surface Area 108.000 Ų Heavy Atom Count 31 Formal Charge 0 Complexity 674.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 1
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