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R18 TFA, CAS No.211364-78-2(free)
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GRADE & PURITY ≥98%
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
application：
R18 trifluoroacetate has been used to treat 12-d-old or 14-d-old Super:C-repeat-binding factors (CBFs)-Myc plants for CBF protein immunoblots to study the effect of R18 on CBF3 degradation in planta.
product description：
R18 trifluoroacetate is a nonphosphorylated peptide. This peptide was originally identified as a high-affinity 14-3-3 ligand by phage display.
Specifications
Product Name
R18 TFA, CAS No.211364-78-2(free)
Synonyms
(3S, 4Z, 6S, 7Z, 9S, 10Z, 12S, 13Z, 15S, 16Z, 18S, 19Z, 21S, 22Z, 24S)-12-((1H-indol-3-yl)methyl)-18-(carboxymethyl)-24-((1Z, 3S, 4Z, 6S, 7Z, 9S, 10Z, 12R, 13Z, 15S)-15-((S)-2-carboxypyrrolidine-1-carbonyl)-1, 4, 7, 10, 13-pentahydroxy-6-(2-hydroxy-2-iminoethyl)-12-(mercaptomethyl)
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
R18 is a competitive inhibitor of the 14-3-3 scaffolding proteins. It binds to the general binding groove of 14-3-3. R18 blocks 14-3-3 interaction with most or all of its client proteins.
R18 (PHCVPRDLSWLDLEANMCLP), a competitive inhibitor of 14-3-3 scaff
Sequence
Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro
CAS
211364-78-2(free)
Molecule Type
Peptide
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2218524 | Certificate of Analysis | Jun 09, 2025 | R407695 |
| H2218525 | Certificate of Analysis | Jun 09, 2025 | R407695 |
| H2218526 | Certificate of Analysis | Jun 09, 2025 | R407695 |
| H2218527 | Certificate of Analysis | Jun 09, 2025 | R407695 |
| H2218528 | Certificate of Analysis | Jun 09, 2025 | R407695 |
| H2218529 | Certificate of Analysis | Jun 09, 2025 | R407695 |
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