GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥95%(SDS-PAGE)See COA
Accession #
O08689
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant human GDF8/Myostatin protein (rp156335) at 1.0 μg/mL can bind Domagrozumab (anti-GDF8) (Ab175511) with the EC50 of 33.4 ng/mL.
ActiBioPure™, Animal Free, Bioactive, Carrier Free, His Tag, PBS Only
Specifications & Purity
Animal Free, Carrier Free, Bioactive, ActiBioPure™, His Tag, PBS Only, ≥95%(SDS-PAGE), See COA
Biochemical and Physiological Mechanisms
GDF-8 / Myostatin / MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing se
Bioactivity
Immobilized Recombinant human GDF8/Myostatin protein (rp156335) at 1.0 μg/mL can bind Domagrozumab (anti-GDF8) (Ab175511) with the EC50 of 33.4 ng/mL.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Images
Recombinant human GDF8 / Myostatin protein (rp156335) - ELISA Immobilized Recombinant human GDF8 / Myostatin protein (rp156335) at 1.0 μg/mL can bind Domagrozumab (anti-GDF8) (Ab175511) with the EC50 of 33.4 ng/mL.
Recombinant human GDF8 / Myostatin protein (rp156335) - SDS-PAGE 3 μg/lane of Recombinant human GDF8 / Myostatin protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 13.8 & 37.2 & 50.3 kDa under reducing.
This protein carries a polyhistidine tag at the N-terminus. The protein migrates as 13.8 kDa, 37.2 kDa and 50.3 kDa when calibrated against Protein Marker under reducing (R) condition (SDS-PAGE), speculated as mature GDF-8, propeptide and latent GDF-8 respectively due to glycosylation.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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